A simple computerized program for the calculation of the required sample size necessary to ensure statistical accuracy in medical experiments

Hitomi Nutahara, Eisuke Hanada, Naoko Kinukawa, Yuko Kenjo, Yasuaki Antoku, Kouhei Akazawa, Yoshiaki Nose

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We developed a sample size estimation program (SSEP) with which medical researchers can easily estimate the appropriate sample size for a specific significance level and statistical power using their favorite WWW browsers. SSEP can estimate the sample sizes for six statistical methods by Monte-Carlo simulation: Student's t-test, Welch's t-test, Analysis of variance, Wilcoxon's rank sum test, Kruskal-Wallis test, and the Cochran-Armitage test for linear trends. The SSEP simulation programs were created using the SAS software macro language. Medical researchers can interactively use this program and determine reliable sample sizes when planning new prospective clinical studies and animal experiments.

Original languageEnglish
Pages (from-to)133-139
Number of pages7
JournalComputer Methods and Programs in Biomedicine
Volume65
Issue number2
DOIs
Publication statusPublished - Mar 28 2001

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Sample Size
Experiments
Nonparametric Statistics
Analysis of variance (ANOVA)
World Wide Web
Macros
Statistical methods
Animals
Research Personnel
Students
Planning
Monte Carlo Method
Analysis of Variance
Language
Software
Prospective Studies
Monte Carlo simulation

All Science Journal Classification (ASJC) codes

  • Software
  • Computer Science Applications
  • Health Informatics

Cite this

A simple computerized program for the calculation of the required sample size necessary to ensure statistical accuracy in medical experiments. / Nutahara, Hitomi; Hanada, Eisuke; Kinukawa, Naoko; Kenjo, Yuko; Antoku, Yasuaki; Akazawa, Kouhei; Nose, Yoshiaki.

In: Computer Methods and Programs in Biomedicine, Vol. 65, No. 2, 28.03.2001, p. 133-139.

Research output: Contribution to journalArticle

Nutahara, Hitomi ; Hanada, Eisuke ; Kinukawa, Naoko ; Kenjo, Yuko ; Antoku, Yasuaki ; Akazawa, Kouhei ; Nose, Yoshiaki. / A simple computerized program for the calculation of the required sample size necessary to ensure statistical accuracy in medical experiments. In: Computer Methods and Programs in Biomedicine. 2001 ; Vol. 65, No. 2. pp. 133-139.
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