A simple model of cell proliferation of bacteria using min oscillation

Hidetsugu Sakaguchi, Yuka Kawasaki

Research output: Contribution to journalArticle

Abstract

A mathematical model of Min oscillation in Escherichia coli is numerically studied. The oscillatory state and hysteretic transition are explained with simpler coupled differential equations. Next, we propose a simple model of cell growth and division using the Min oscillation. The cell cycle is not constant but exhibits fluctuation in the deterministic model. Finally, we perform direct numerical simulation of cell assemblies composed of many cells obeying the simple growth and division model. As the cell number increases with time, the spatial distribution of cell assembly becomes more circular, although the cells are aligned almost in the x-direction.

Original languageEnglish
Article number104002
Journaljournal of the physical society of japan
Volume88
Issue number10
DOIs
Publication statusPublished - Jan 1 2019

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bacteria
oscillations
cells
division
Escherichia
direct numerical simulation
assemblies
mathematical models
spatial distribution
differential equations
assembly
cycles

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

Cite this

A simple model of cell proliferation of bacteria using min oscillation. / Sakaguchi, Hidetsugu; Kawasaki, Yuka.

In: journal of the physical society of japan, Vol. 88, No. 10, 104002, 01.01.2019.

Research output: Contribution to journalArticle

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