A simplified method of T1ρ mapping in clinical assessment of knee joint

Yukihisa Takayama, Masamitsu Hatakenaka, Takashi Yoshiura, Ken Okazaki, Kei Nishikawa, Tomoyuki Okuaki, Ivan Zimine, Hiroshi Honda

Research output: Contribution to journalArticle

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Abstract

Purpose: We assessed the clinical utility of our proposed simplified method for TT1ρ mapping calculations. Materials and Methods: Ten healthy subjects underwent scanning on a 3-tesla magnetic resonance system using an 8-channel phased-array coil. For each subject, we obtained sagittal T1ρ-prepared images using 5 different time of spin-lock pulses (TSL=1, 20, 40, 60, and 80 ms), produced conventional TT1ρ maps (cT1ρ maps) using all TSLs, and recomputed our proposed simplified T1ρ maps (sT1ρ maps) using a decreasing number of TSLs (from 4 to 2). We then investigated the differences and correlations in T1ρ values of the tissues obtained using different numbers of spin-lock times. Results: There was a strong positive correlation (single measure intraclass correlation coefficient=0.948; 95z confidence interval=0.911 to 0.970) in T1ρ values of tissues between the cT1ρ and sT1ρ [1, 80] maps. The 2 maps were comparable, though there was a small difference in T1ρ value between the two. The total scan time to acquire the data from 5 spin-lock times was 16 min 15 s. Similarity of the T1ρ [1, 80] map with the conventional approach reduced scan time by 60z, to 6min 30 s. Conclusion: The clinical relevance of our proposed simplified method is potentially similar to that of the conventional method, and our method requires a shorter examination time and generally preserves the reliability of the T1ρ relaxation time of the tissues.

Original languageEnglish
Pages (from-to)209-215
Number of pages7
JournalMagnetic Resonance in Medical Sciences
Volume9
Issue number4
DOIs
Publication statusPublished - Dec 1 2010

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Knee Joint
Healthy Volunteers
Magnetic Resonance Spectroscopy
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Takayama, Y., Hatakenaka, M., Yoshiura, T., Okazaki, K., Nishikawa, K., Okuaki, T., ... Honda, H. (2010). A simplified method of T1ρ mapping in clinical assessment of knee joint. Magnetic Resonance in Medical Sciences, 9(4), 209-215. https://doi.org/10.2463/mrms.9.209

A simplified method of T1ρ mapping in clinical assessment of knee joint. / Takayama, Yukihisa; Hatakenaka, Masamitsu; Yoshiura, Takashi; Okazaki, Ken; Nishikawa, Kei; Okuaki, Tomoyuki; Zimine, Ivan; Honda, Hiroshi.

In: Magnetic Resonance in Medical Sciences, Vol. 9, No. 4, 01.12.2010, p. 209-215.

Research output: Contribution to journalArticle

Takayama, Y, Hatakenaka, M, Yoshiura, T, Okazaki, K, Nishikawa, K, Okuaki, T, Zimine, I & Honda, H 2010, 'A simplified method of T1ρ mapping in clinical assessment of knee joint', Magnetic Resonance in Medical Sciences, vol. 9, no. 4, pp. 209-215. https://doi.org/10.2463/mrms.9.209
Takayama, Yukihisa ; Hatakenaka, Masamitsu ; Yoshiura, Takashi ; Okazaki, Ken ; Nishikawa, Kei ; Okuaki, Tomoyuki ; Zimine, Ivan ; Honda, Hiroshi. / A simplified method of T1ρ mapping in clinical assessment of knee joint. In: Magnetic Resonance in Medical Sciences. 2010 ; Vol. 9, No. 4. pp. 209-215.
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