A single bacterium and mammalian cell analysis by ionic current measurements in a microchannel

Noritada Kaji, M. Sano, S. Ito, H. Yasaki, T. Yasui, H. Yukawa, Y. Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A microfluidic device based on ionic current detection system for high-throughput and practical single bacteria and mammalian cell sizing was developed, and furthermore, discrimination of bacterial species and mammalian cell deformability was achieved. The highly precise sizing system based on blocking ionic current at narrow microchannel provided the information on antibiotic resistant strains of bacteria. Deformability changes associated with passage of adipose tissue-derived stem cells (ASCs) were also successfully detected by the device without any chemical or biological modification.

Original languageEnglish
Title of host publication2017 IEEE International Electron Devices Meeting, IEDM 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages10.3.1-10.3.4
ISBN (Electronic)9781538635599
DOIs
Publication statusPublished - Jan 23 2018
Externally publishedYes
Event63rd IEEE International Electron Devices Meeting, IEDM 2017 - San Francisco, United States
Duration: Dec 2 2017Dec 6 2017

Publication series

NameTechnical Digest - International Electron Devices Meeting, IEDM
ISSN (Print)0163-1918

Other

Other63rd IEEE International Electron Devices Meeting, IEDM 2017
CountryUnited States
CitySan Francisco
Period12/2/1712/6/17

Fingerprint

sizing
Electric current measurement
Formability
microchannels
Microchannels
bacteria
Bacteria
Cells
adipose tissues
stem cells
antibiotics
microfluidic devices
Antibiotics
Stem cells
Microfluidics
discrimination
Throughput
Tissue
Anti-Bacterial Agents

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Electrical and Electronic Engineering
  • Materials Chemistry

Cite this

Kaji, N., Sano, M., Ito, S., Yasaki, H., Yasui, T., Yukawa, H., & Baba, Y. (2018). A single bacterium and mammalian cell analysis by ionic current measurements in a microchannel. In 2017 IEEE International Electron Devices Meeting, IEDM 2017 (pp. 10.3.1-10.3.4). (Technical Digest - International Electron Devices Meeting, IEDM). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IEDM.2017.8268363

A single bacterium and mammalian cell analysis by ionic current measurements in a microchannel. / Kaji, Noritada; Sano, M.; Ito, S.; Yasaki, H.; Yasui, T.; Yukawa, H.; Baba, Y.

2017 IEEE International Electron Devices Meeting, IEDM 2017. Institute of Electrical and Electronics Engineers Inc., 2018. p. 10.3.1-10.3.4 (Technical Digest - International Electron Devices Meeting, IEDM).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kaji, N, Sano, M, Ito, S, Yasaki, H, Yasui, T, Yukawa, H & Baba, Y 2018, A single bacterium and mammalian cell analysis by ionic current measurements in a microchannel. in 2017 IEEE International Electron Devices Meeting, IEDM 2017. Technical Digest - International Electron Devices Meeting, IEDM, Institute of Electrical and Electronics Engineers Inc., pp. 10.3.1-10.3.4, 63rd IEEE International Electron Devices Meeting, IEDM 2017, San Francisco, United States, 12/2/17. https://doi.org/10.1109/IEDM.2017.8268363
Kaji N, Sano M, Ito S, Yasaki H, Yasui T, Yukawa H et al. A single bacterium and mammalian cell analysis by ionic current measurements in a microchannel. In 2017 IEEE International Electron Devices Meeting, IEDM 2017. Institute of Electrical and Electronics Engineers Inc. 2018. p. 10.3.1-10.3.4. (Technical Digest - International Electron Devices Meeting, IEDM). https://doi.org/10.1109/IEDM.2017.8268363
Kaji, Noritada ; Sano, M. ; Ito, S. ; Yasaki, H. ; Yasui, T. ; Yukawa, H. ; Baba, Y. / A single bacterium and mammalian cell analysis by ionic current measurements in a microchannel. 2017 IEEE International Electron Devices Meeting, IEDM 2017. Institute of Electrical and Electronics Engineers Inc., 2018. pp. 10.3.1-10.3.4 (Technical Digest - International Electron Devices Meeting, IEDM).
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