A six-membered ball-like supramolecular structure of 1c was obtained by the interplay of hydrophobic and hydrogen bonding interactions. Preferred H-bonding connectivity and the proximate side-chain groups in a hydrophobic core stabilized to form the ball structure as revealed by making a comparison with the linear tape structure in the crystal polymorph of 1c.
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry