A stereoselective synthesis of cyclohexylnorstatine, the key component of a renin inhibitor

Teruyo Matsumoto, Yuko Kobayashi, Yoshiji Takemoto, Yoshio Ito, Tetsuhide Kamijo, Hiromu Harada, Shiro Terashima

Research output: Contribution to journalArticlepeer-review

50 Citations (Scopus)

Abstract

The title synthesis could be accomplished by employing the novel addition reaction of a Grignard reagent with an imine in the presence of cerium(III) chloride.

Original languageEnglish
Pages (from-to)4175-4176
Number of pages2
JournalTetrahedron Letters
Volume31
Issue number29
DOIs
Publication statusPublished - 1990
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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