A study of the association between the prognosis of carcinoma of the mandibular gingiva and the pattern of bone destruction on computed tomography

E. Nakayama, Kazunori Yoshiura, K. Yuasa, S. Kanda, M. Saitoh, W. Kage, T. Ikebe, S. Ozeki, M. Shinohara

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

To clarify whether the pattern of bone destruction seen on CT is more closely associated with the outcome of carcinoma of the mandibular gingiva than that derived from panoramic radiographs (PR). Axial bone window CT scans and PR of 62 patients with carcinoma of the mandibular gingiva were evaluated retrospectively by two oral radiologists for the pattern of bone destruction. Patterns were classified into the three types: erosive, invasive and mixed. The relationship between these patterns with each imaging modality and cumulative recurrence rate, cumulative metastasis rate and cumulative survival rate, calculated by the Kaplan-Meier method, were statistically analysed by the log rank test. The pattern of bone destruction derived from CT was closely associated with the cumulative metastasis rate (P<0.05), the cumulative recurrence rate and the cumulative survival rate. In contrast, the pattern of bone destruction based on the PR was not associated with the cumulative metastasis rate (P = 0.43), the cumulative recurrence rate (P = 0.44), or the cumulative survival rate (P = 0.5). The prognosis of patients with carcinoma of the mandibular gingiva is more closely related to a classification derived from the pattern of bone destruction on CT rather than PR. However, the number of subjects investigated in this study was not large enough to confirm our conclusions statistically. Further studies by other investigators are therefore needed.

Original languageEnglish
Pages (from-to)163-169
Number of pages7
JournalDentomaxillofacial Radiology
Volume29
Issue number3
DOIs
Publication statusPublished - Jan 1 2000

Fingerprint

Gingiva
Tomography
Carcinoma
Bone and Bones
Survival Rate
Neoplasm Metastasis
Recurrence
Research Personnel

All Science Journal Classification (ASJC) codes

  • Otorhinolaryngology
  • Radiology Nuclear Medicine and imaging
  • Dentistry(all)

Cite this

A study of the association between the prognosis of carcinoma of the mandibular gingiva and the pattern of bone destruction on computed tomography. / Nakayama, E.; Yoshiura, Kazunori; Yuasa, K.; Kanda, S.; Saitoh, M.; Kage, W.; Ikebe, T.; Ozeki, S.; Shinohara, M.

In: Dentomaxillofacial Radiology, Vol. 29, No. 3, 01.01.2000, p. 163-169.

Research output: Contribution to journalArticle

Nakayama, E. ; Yoshiura, Kazunori ; Yuasa, K. ; Kanda, S. ; Saitoh, M. ; Kage, W. ; Ikebe, T. ; Ozeki, S. ; Shinohara, M. / A study of the association between the prognosis of carcinoma of the mandibular gingiva and the pattern of bone destruction on computed tomography. In: Dentomaxillofacial Radiology. 2000 ; Vol. 29, No. 3. pp. 163-169.
@article{ec675bb66ce247bebd52ad76ee17412f,
title = "A study of the association between the prognosis of carcinoma of the mandibular gingiva and the pattern of bone destruction on computed tomography",
abstract = "To clarify whether the pattern of bone destruction seen on CT is more closely associated with the outcome of carcinoma of the mandibular gingiva than that derived from panoramic radiographs (PR). Axial bone window CT scans and PR of 62 patients with carcinoma of the mandibular gingiva were evaluated retrospectively by two oral radiologists for the pattern of bone destruction. Patterns were classified into the three types: erosive, invasive and mixed. The relationship between these patterns with each imaging modality and cumulative recurrence rate, cumulative metastasis rate and cumulative survival rate, calculated by the Kaplan-Meier method, were statistically analysed by the log rank test. The pattern of bone destruction derived from CT was closely associated with the cumulative metastasis rate (P<0.05), the cumulative recurrence rate and the cumulative survival rate. In contrast, the pattern of bone destruction based on the PR was not associated with the cumulative metastasis rate (P = 0.43), the cumulative recurrence rate (P = 0.44), or the cumulative survival rate (P = 0.5). The prognosis of patients with carcinoma of the mandibular gingiva is more closely related to a classification derived from the pattern of bone destruction on CT rather than PR. However, the number of subjects investigated in this study was not large enough to confirm our conclusions statistically. Further studies by other investigators are therefore needed.",
author = "E. Nakayama and Kazunori Yoshiura and K. Yuasa and S. Kanda and M. Saitoh and W. Kage and T. Ikebe and S. Ozeki and M. Shinohara",
year = "2000",
month = "1",
day = "1",
doi = "10.1038/sj.dmfr.4600527",
language = "English",
volume = "29",
pages = "163--169",
journal = "Dentomaxillofacial Radiology",
issn = "0250-832X",
publisher = "British Institute of Radiology",
number = "3",

}

TY - JOUR

T1 - A study of the association between the prognosis of carcinoma of the mandibular gingiva and the pattern of bone destruction on computed tomography

AU - Nakayama, E.

AU - Yoshiura, Kazunori

AU - Yuasa, K.

AU - Kanda, S.

AU - Saitoh, M.

AU - Kage, W.

AU - Ikebe, T.

AU - Ozeki, S.

AU - Shinohara, M.

PY - 2000/1/1

Y1 - 2000/1/1

N2 - To clarify whether the pattern of bone destruction seen on CT is more closely associated with the outcome of carcinoma of the mandibular gingiva than that derived from panoramic radiographs (PR). Axial bone window CT scans and PR of 62 patients with carcinoma of the mandibular gingiva were evaluated retrospectively by two oral radiologists for the pattern of bone destruction. Patterns were classified into the three types: erosive, invasive and mixed. The relationship between these patterns with each imaging modality and cumulative recurrence rate, cumulative metastasis rate and cumulative survival rate, calculated by the Kaplan-Meier method, were statistically analysed by the log rank test. The pattern of bone destruction derived from CT was closely associated with the cumulative metastasis rate (P<0.05), the cumulative recurrence rate and the cumulative survival rate. In contrast, the pattern of bone destruction based on the PR was not associated with the cumulative metastasis rate (P = 0.43), the cumulative recurrence rate (P = 0.44), or the cumulative survival rate (P = 0.5). The prognosis of patients with carcinoma of the mandibular gingiva is more closely related to a classification derived from the pattern of bone destruction on CT rather than PR. However, the number of subjects investigated in this study was not large enough to confirm our conclusions statistically. Further studies by other investigators are therefore needed.

AB - To clarify whether the pattern of bone destruction seen on CT is more closely associated with the outcome of carcinoma of the mandibular gingiva than that derived from panoramic radiographs (PR). Axial bone window CT scans and PR of 62 patients with carcinoma of the mandibular gingiva were evaluated retrospectively by two oral radiologists for the pattern of bone destruction. Patterns were classified into the three types: erosive, invasive and mixed. The relationship between these patterns with each imaging modality and cumulative recurrence rate, cumulative metastasis rate and cumulative survival rate, calculated by the Kaplan-Meier method, were statistically analysed by the log rank test. The pattern of bone destruction derived from CT was closely associated with the cumulative metastasis rate (P<0.05), the cumulative recurrence rate and the cumulative survival rate. In contrast, the pattern of bone destruction based on the PR was not associated with the cumulative metastasis rate (P = 0.43), the cumulative recurrence rate (P = 0.44), or the cumulative survival rate (P = 0.5). The prognosis of patients with carcinoma of the mandibular gingiva is more closely related to a classification derived from the pattern of bone destruction on CT rather than PR. However, the number of subjects investigated in this study was not large enough to confirm our conclusions statistically. Further studies by other investigators are therefore needed.

UR - http://www.scopus.com/inward/record.url?scp=0034189258&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034189258&partnerID=8YFLogxK

U2 - 10.1038/sj.dmfr.4600527

DO - 10.1038/sj.dmfr.4600527

M3 - Article

C2 - 10849543

AN - SCOPUS:0034189258

VL - 29

SP - 163

EP - 169

JO - Dentomaxillofacial Radiology

JF - Dentomaxillofacial Radiology

SN - 0250-832X

IS - 3

ER -