A successful resection and long-term survival of a patient with intrahepatic recurrences of combined hepatocellular-cholangiocarcinoma: Report of a case

Hidetoshi Eguchi, Hiroaki Nagano, Masato Sakon, Atsushi Miyamoto, Motoi Kondo, Isao Arai, Osakuni Morimoto, Keizo Dono, Koji Umeshita, Shoji Nakamori, Kenichi Wakasa, Morito Monden

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Because of the low incidence rate of combined hepatocellular-cholangiocarcinoma (combined HCC-CC), the clinicopathological features of a recurrent tumor of this disease remain to be elucidated. We describe a 47-year-old Japanese woman with a 5-cm diameter mass lesion in the liver. A hepatectomy and dissection of the local lymph nodes were performed and a histological examination of the resected specimen showed combined HCC-CC. After a follow-up of 15 months, intrahepatic recurrence was observed, and a hepatectomy was performed again followed by hepatic arterial infusion chemotherapy. A histological examination revealed that the recurrent tumors consisted of only cholangioacarcinoma. A disease-free survival was obtained for about 7 years after the recurrence. To improve the poor prognosis of combined HCC-CC, clinicopathological features of this disease and the therapy selection for recurrent tumors should be discussed.

Original languageEnglish
Pages (from-to)742-746
Number of pages5
JournalSurgery today
Issue number8
Publication statusPublished - Sep 20 2002


All Science Journal Classification (ASJC) codes

  • Surgery

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