TY - JOUR
T1 - A tetranuclear-zinc-cluster-catalyzed practical and versatile deprotection of acetates and benzoates
AU - Iwasaki, Takanori
AU - Agura, Kazushi
AU - Maegawa, Yusuke
AU - Hayashi, Yukiko
AU - Ohshima, Takashi
AU - Mashima, Kazushi
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2010/10/11
Y1 - 2010/10/11
N2 - A new catalytic deacylation of acetates and benzoates through transesterification with methanol was developed (see scheme). Reactions with various acidand nucleophile-sensitive functional groups proceeded efficiently in the presence of a catalytic amount of the tetranuclear zinc cluster. The present catalysis is applicable to less-reactive tertiary acetates, the deacylation of which is difficult to achieve by transesterification with other catalysts.
AB - A new catalytic deacylation of acetates and benzoates through transesterification with methanol was developed (see scheme). Reactions with various acidand nucleophile-sensitive functional groups proceeded efficiently in the presence of a catalytic amount of the tetranuclear zinc cluster. The present catalysis is applicable to less-reactive tertiary acetates, the deacylation of which is difficult to achieve by transesterification with other catalysts.
UR - http://www.scopus.com/inward/record.url?scp=77957582085&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77957582085&partnerID=8YFLogxK
U2 - 10.1002/chem.201000960
DO - 10.1002/chem.201000960
M3 - Article
C2 - 20799300
AN - SCOPUS:77957582085
VL - 16
SP - 11567
EP - 11571
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
SN - 0947-6539
IS - 38
ER -