Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering

R. B. Diego; M. P. Olmedilla; Á S. Aroca; J. L.G. Ribelles; M. M. Pradas; G. G. Ferrer; M. S. Sánchez

doi:10.1007/s10853-005-3885-4

Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering

R. B. Diego, M. P. Olmedilla, Á S. Aroca, J. L.G. Ribelles, M. M. Pradas, G. G. Ferrer, M. S. Sánchez

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.

Original language	English
Pages (from-to)	4881-4887
Number of pages	7
Journal	Journal of Materials Science
Volume	40
Issue number	18
DOIs	https://doi.org/10.1007/s10853-005-3885-4
Publication status	Published - Sept 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.1007/s10853-005-3885-4

Cite this

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title = "Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering",

abstract = "Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.",

author = "Diego, {R. B.} and Olmedilla, {M. P.} and Aroca, {{\'A} S.} and Ribelles, {J. L.G.} and Pradas, {M. M.} and Ferrer, {G. G.} and S{\'a}nchez, {M. S.}",

note = "Funding Information: This work was supported by the Spanish Science and Technology Ministry through the MAT2001-2678-C02-01 project.",

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doi = "10.1007/s10853-005-3885-4",

language = "English",

volume = "40",

pages = "4881--4887",

journal = "Journal of Materials Science",

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publisher = "Springer Netherlands",

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T1 - Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering

AU - Diego, R. B.

AU - Olmedilla, M. P.

AU - Aroca, Á S.

AU - Ribelles, J. L.G.

AU - Pradas, M. M.

AU - Ferrer, G. G.

AU - Sánchez, M. S.

N1 - Funding Information: This work was supported by the Spanish Science and Technology Ministry through the MAT2001-2678-C02-01 project.

PY - 2005/9

Y1 - 2005/9

N2 - Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.

AB - Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.

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Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering

Abstract

All Science Journal Classification (ASJC) codes

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