Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering

R. B. Diego, M. P. Olmedilla, Á S. Aroca, J. L.G. Ribelles, M. M. Pradas, G. G. Ferrer, M. S. Sánchez

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.

Original languageEnglish
Pages (from-to)4881-4887
Number of pages7
JournalJournal of Materials Science
Volume40
Issue number18
DOIs
Publication statusPublished - Sep 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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