Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering

R. Brígido Diego, M. Pérez Olmedilla, A. Serrano Aroca, J. L. Gómez Ribelles, M. Monleón Pradas, G. Gallego Ferrer, M. Salmerón Sánchez

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.

Original languageEnglish
Pages (from-to)693-698
Number of pages6
JournalJournal of Materials Science: Materials in Medicine
Volume16
Issue number8
DOIs
Publication statusPublished - Aug 1 2005
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

Fingerprint Dive into the research topics of 'Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering'. Together they form a unique fingerprint.

  • Cite this

    Brígido Diego, R., Pérez Olmedilla, M., Serrano Aroca, A., Gómez Ribelles, J. L., Monleón Pradas, M., Gallego Ferrer, G., & Salmerón Sánchez, M. (2005). Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering. Journal of Materials Science: Materials in Medicine, 16(8), 693-698. https://doi.org/10.1007/s10856-005-2604-7