Active self-organization of microtubules in an inert chamber system

Arif Md Rashedul Kabir, Daisuke Inoue, Akira Kakugo, Kazuki Sada, Jian Ping Gong

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Microtubule-kinesin system is considered as a building block for the construction of artificial biomachines, and active self-organization of microtubules has been used to integrate their structural organization and achieve amplified functions similar to those observed in natural systems. However, the short lifetime of assembled structures has limited their use in organized systems. In the present study, we demonstrated that the use of an inert atmosphere in the self-organization of microtubules allows the assembled structures to remain active for a prolonged period of time (10 times longer). The longer lifetime achieved in the present study will facilitate the development of assembled microtubules for designing biomolecular motor-based efficient artificial biomachines with prolonged lifetimes.

Original languageEnglish
Pages (from-to)607-611
Number of pages5
JournalPolymer Journal
Volume44
Issue number6
DOIs
Publication statusPublished - Jun 1 2012
Externally publishedYes

Fingerprint

Kinesin

All Science Journal Classification (ASJC) codes

  • Polymers and Plastics
  • Materials Chemistry

Cite this

Active self-organization of microtubules in an inert chamber system. / Kabir, Arif Md Rashedul; Inoue, Daisuke; Kakugo, Akira; Sada, Kazuki; Gong, Jian Ping.

In: Polymer Journal, Vol. 44, No. 6, 01.06.2012, p. 607-611.

Research output: Contribution to journalArticle

Kabir, Arif Md Rashedul ; Inoue, Daisuke ; Kakugo, Akira ; Sada, Kazuki ; Gong, Jian Ping. / Active self-organization of microtubules in an inert chamber system. In: Polymer Journal. 2012 ; Vol. 44, No. 6. pp. 607-611.
@article{7d53d01bdeca47abbd34eea46db61d3e,
title = "Active self-organization of microtubules in an inert chamber system",
abstract = "Microtubule-kinesin system is considered as a building block for the construction of artificial biomachines, and active self-organization of microtubules has been used to integrate their structural organization and achieve amplified functions similar to those observed in natural systems. However, the short lifetime of assembled structures has limited their use in organized systems. In the present study, we demonstrated that the use of an inert atmosphere in the self-organization of microtubules allows the assembled structures to remain active for a prolonged period of time (10 times longer). The longer lifetime achieved in the present study will facilitate the development of assembled microtubules for designing biomolecular motor-based efficient artificial biomachines with prolonged lifetimes.",
author = "Kabir, {Arif Md Rashedul} and Daisuke Inoue and Akira Kakugo and Kazuki Sada and Gong, {Jian Ping}",
year = "2012",
month = "6",
day = "1",
doi = "10.1038/pj.2012.26",
language = "English",
volume = "44",
pages = "607--611",
journal = "Polymer Journal",
issn = "0032-3896",
publisher = "Nature Publishing Group",
number = "6",

}

TY - JOUR

T1 - Active self-organization of microtubules in an inert chamber system

AU - Kabir, Arif Md Rashedul

AU - Inoue, Daisuke

AU - Kakugo, Akira

AU - Sada, Kazuki

AU - Gong, Jian Ping

PY - 2012/6/1

Y1 - 2012/6/1

N2 - Microtubule-kinesin system is considered as a building block for the construction of artificial biomachines, and active self-organization of microtubules has been used to integrate their structural organization and achieve amplified functions similar to those observed in natural systems. However, the short lifetime of assembled structures has limited their use in organized systems. In the present study, we demonstrated that the use of an inert atmosphere in the self-organization of microtubules allows the assembled structures to remain active for a prolonged period of time (10 times longer). The longer lifetime achieved in the present study will facilitate the development of assembled microtubules for designing biomolecular motor-based efficient artificial biomachines with prolonged lifetimes.

AB - Microtubule-kinesin system is considered as a building block for the construction of artificial biomachines, and active self-organization of microtubules has been used to integrate their structural organization and achieve amplified functions similar to those observed in natural systems. However, the short lifetime of assembled structures has limited their use in organized systems. In the present study, we demonstrated that the use of an inert atmosphere in the self-organization of microtubules allows the assembled structures to remain active for a prolonged period of time (10 times longer). The longer lifetime achieved in the present study will facilitate the development of assembled microtubules for designing biomolecular motor-based efficient artificial biomachines with prolonged lifetimes.

UR - http://www.scopus.com/inward/record.url?scp=84861941546&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861941546&partnerID=8YFLogxK

U2 - 10.1038/pj.2012.26

DO - 10.1038/pj.2012.26

M3 - Article

AN - SCOPUS:84861941546

VL - 44

SP - 607

EP - 611

JO - Polymer Journal

JF - Polymer Journal

SN - 0032-3896

IS - 6

ER -