Abstract
The toxicity of three pharmaceutical and personal care products (PPCPs) - carbamazepine (CBMZ), diclofenac (DCF), and triclosan (TCS) - was examined by measuring their effects on feeding behavior and swimming speed of adult Japanese medaka fish (Oryzias latipes). Medaka were exposed to 6.15mgL -1 CBMZ, 1.0mgL -1 DCF, 0.17mgL -1 TCS, or no PPCP (control) for 9d. Fish behaviors were monitored during days 5-9 of the exposure period. Feeding behavior (time to eat midge larvae, TE) and swimming speed (SS) of individual exposed and control fish were tracked in two dimensions, using an automated system with a digital charge-coupled device camera. As a result, feeding behavior was affected by exposure to CBMZ and DCF, while SS was altered by exposure to CBMZ and TCS. Thus, TCS, DCF and CBMZ appear to affect fish behaviors through different mechanisms. Overall, the results suggest that behavioral changes may provide a sensitive indicator for assessing the toxicity of PPCPs to aquatic organisms.
| Original language | English |
|---|---|
| Pages (from-to) | 1095-1100 |
| Number of pages | 6 |
| Journal | Chemosphere |
| Volume | 80 |
| Issue number | 9 |
| DOIs | |
| Publication status | Published - Aug 1 2010 |
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All Science Journal Classification (ASJC) codes
- Environmental Chemistry
- Chemistry(all)
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Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes). / Nassef, Mohamed; Matsumoto, Shuhei; Seki, Masanori; Khalil, Fatma; Kang, Ikjoon; Shimasaki, Yohei; Oshima, Yuji; Honjo, Tsuneo.
In: Chemosphere, Vol. 80, No. 9, 01.08.2010, p. 1095-1100.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes)
AU - Nassef, Mohamed
AU - Matsumoto, Shuhei
AU - Seki, Masanori
AU - Khalil, Fatma
AU - Kang, Ikjoon
AU - Shimasaki, Yohei
AU - Oshima, Yuji
AU - Honjo, Tsuneo
PY - 2010/8/1
Y1 - 2010/8/1
N2 - The toxicity of three pharmaceutical and personal care products (PPCPs) - carbamazepine (CBMZ), diclofenac (DCF), and triclosan (TCS) - was examined by measuring their effects on feeding behavior and swimming speed of adult Japanese medaka fish (Oryzias latipes). Medaka were exposed to 6.15mgL -1 CBMZ, 1.0mgL -1 DCF, 0.17mgL -1 TCS, or no PPCP (control) for 9d. Fish behaviors were monitored during days 5-9 of the exposure period. Feeding behavior (time to eat midge larvae, TE) and swimming speed (SS) of individual exposed and control fish were tracked in two dimensions, using an automated system with a digital charge-coupled device camera. As a result, feeding behavior was affected by exposure to CBMZ and DCF, while SS was altered by exposure to CBMZ and TCS. Thus, TCS, DCF and CBMZ appear to affect fish behaviors through different mechanisms. Overall, the results suggest that behavioral changes may provide a sensitive indicator for assessing the toxicity of PPCPs to aquatic organisms.
AB - The toxicity of three pharmaceutical and personal care products (PPCPs) - carbamazepine (CBMZ), diclofenac (DCF), and triclosan (TCS) - was examined by measuring their effects on feeding behavior and swimming speed of adult Japanese medaka fish (Oryzias latipes). Medaka were exposed to 6.15mgL -1 CBMZ, 1.0mgL -1 DCF, 0.17mgL -1 TCS, or no PPCP (control) for 9d. Fish behaviors were monitored during days 5-9 of the exposure period. Feeding behavior (time to eat midge larvae, TE) and swimming speed (SS) of individual exposed and control fish were tracked in two dimensions, using an automated system with a digital charge-coupled device camera. As a result, feeding behavior was affected by exposure to CBMZ and DCF, while SS was altered by exposure to CBMZ and TCS. Thus, TCS, DCF and CBMZ appear to affect fish behaviors through different mechanisms. Overall, the results suggest that behavioral changes may provide a sensitive indicator for assessing the toxicity of PPCPs to aquatic organisms.
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UR - http://www.scopus.com/inward/citedby.url?scp=77955171102&partnerID=8YFLogxK
U2 - 10.1016/j.chemosphere.2010.04.073
DO - 10.1016/j.chemosphere.2010.04.073
M3 - Article
VL - 80
SP - 1095
EP - 1100
JO - Chemosphere
JF - Chemosphere
SN - 0045-6535
IS - 9
ER -