Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes)

Mohamed Nassef, Shuhei Matsumoto, Masanori Seki, Fatma Khalil, Ikjoon Kang, Yohei Shimasaki, Yuji Oshima, Tsuneo Honjo

Research output: Contribution to journalArticle

107 Citations (Scopus)

Abstract

The toxicity of three pharmaceutical and personal care products (PPCPs) - carbamazepine (CBMZ), diclofenac (DCF), and triclosan (TCS) - was examined by measuring their effects on feeding behavior and swimming speed of adult Japanese medaka fish (Oryzias latipes). Medaka were exposed to 6.15mgL -1 CBMZ, 1.0mgL -1 DCF, 0.17mgL -1 TCS, or no PPCP (control) for 9d. Fish behaviors were monitored during days 5-9 of the exposure period. Feeding behavior (time to eat midge larvae, TE) and swimming speed (SS) of individual exposed and control fish were tracked in two dimensions, using an automated system with a digital charge-coupled device camera. As a result, feeding behavior was affected by exposure to CBMZ and DCF, while SS was altered by exposure to CBMZ and TCS. Thus, TCS, DCF and CBMZ appear to affect fish behaviors through different mechanisms. Overall, the results suggest that behavioral changes may provide a sensitive indicator for assessing the toxicity of PPCPs to aquatic organisms.

Original languageEnglish
Pages (from-to)1095-1100
Number of pages6
JournalChemosphere
Volume80
Issue number9
DOIs
Publication statusPublished - Aug 1 2010

Fingerprint

Triclosan
Oryzias
Diclofenac
Carbamazepine
Fish
Fishes
feeding behavior
Pharmaceutical Services
Drug products
Feeding Behavior
fish
Toxicity
toxicity
Aquatic organisms
Pharmaceutical Preparations
Digital cameras
CCD cameras
aquatic organism
Aquatic Organisms
Larva

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Chemistry(all)

Cite this

Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes). / Nassef, Mohamed; Matsumoto, Shuhei; Seki, Masanori; Khalil, Fatma; Kang, Ikjoon; Shimasaki, Yohei; Oshima, Yuji; Honjo, Tsuneo.

In: Chemosphere, Vol. 80, No. 9, 01.08.2010, p. 1095-1100.

Research output: Contribution to journalArticle

Nassef, Mohamed ; Matsumoto, Shuhei ; Seki, Masanori ; Khalil, Fatma ; Kang, Ikjoon ; Shimasaki, Yohei ; Oshima, Yuji ; Honjo, Tsuneo. / Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes). In: Chemosphere. 2010 ; Vol. 80, No. 9. pp. 1095-1100.
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