TY - JOUR
T1 - Acute myelitis associated with hyperIgEemia and atopic dermatitis
AU - Kira, Jun ichi
AU - Yamasaki, Kenji
AU - Kawano, Yuji
AU - Kobayashi, Takuro
N1 - Funding Information:
We thank Dr. Masaaki Katsuki for referring one of the patients to us. This work was supported in part by grants from the Neuroimmunological Disease Research Committee, the Ministry of Health and Welfare of Japan, and from the Ministry of Education, Science, Sports and Culture of Japan (No. 08670712).
Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 1997/5/29
Y1 - 1997/5/29
N2 - We herein describe 4 adult patients with upper cervical myelitis presenting with paresthesia in the distal parts of all four limbs and who also all had hyperIgEemia. Two of them had full-blown atopic dermatitis at the time of neurologic illness, while the others had a preceding history of atopic dermatitis. All showed high signal intensity lesions at either the C3 or C4 segment, which mainly affected the posterior column on the T2-weighted spinal cord magnetic resonance imaging. All patients had specific IgE antibodies to two mite antigens and their onset of myelitis coincided with the seasonal increase of the mite antigens in Japan. Therefore, it is possible that the atopic conditions with hyperIgEemia in these patients may thus have contributed to the development of myelitis.
AB - We herein describe 4 adult patients with upper cervical myelitis presenting with paresthesia in the distal parts of all four limbs and who also all had hyperIgEemia. Two of them had full-blown atopic dermatitis at the time of neurologic illness, while the others had a preceding history of atopic dermatitis. All showed high signal intensity lesions at either the C3 or C4 segment, which mainly affected the posterior column on the T2-weighted spinal cord magnetic resonance imaging. All patients had specific IgE antibodies to two mite antigens and their onset of myelitis coincided with the seasonal increase of the mite antigens in Japan. Therefore, it is possible that the atopic conditions with hyperIgEemia in these patients may thus have contributed to the development of myelitis.
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U2 - 10.1016/S0022-510X(97)05369-0
DO - 10.1016/S0022-510X(97)05369-0
M3 - Article
C2 - 9129117
AN - SCOPUS:0031589957
VL - 148
SP - 199
EP - 203
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
SN - 0022-510X
IS - 2
ER -