Acute retinal necrosis: Factors associated with anatomic and visual outcomes

Chiharu Iwahashi-Shima, Atsushi Azumi, Nobuyuki Ohguro, Annabelle A. Okada, Toshikatsu Kaburaki, Hiroshi Goto, Kohei Sonoda, Kenichi Namba, Nobuhisa Mizuki, Manabu Mochizuki

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Purpose: To examine the factors associated with anatomic and visual outcomes in Japanese patients with acute retinal necrosis (ARN). Methods: One hundred four patients with ARN who were followed for more than 1 year at nine referral centers were reviewed. Retinal involvement at initial presentation was classified into four groups: zone 1 (posterior pole, n = 22), zone 2 (midperiphery, n = 54), zone 3 (periphery, n = 25), and unknown (n = 3). Forty-eight eyes underwent prophylactic vitrectomy before development of retinal detachment (vitrectomy group); 56 eyes were treated conventionally without prophylactic vitrectomy (observation group). Results: The retina was attached in 28 of 48 eyes (58.3 %) in the vitrectomy group and 42 of 56 eyes (75.0 %) in the observation group at the final visit (P = 0.071). At 1 year, 56 eyes (53.8 %) had a best-corrected visual acuity (BCVA) of 20/200 or worse. Multivariate logistic regression analyses identified zone 1 disease (odds ratio = 4.983) and optic nerve involvement (odds ratio = 5.084) as significantly associated with BCVA of 20/200 or worse. Among the zone 3 eyes, significantly (P = 0.012) more eyes in the observation group than in the vitrectomy group had an attached retina. Conclusions: Prophylactic vitrectomy did not improve the final BCVA in any eyes. Zone 3 eyes had better outcomes without prophylactic vitrectomy.

Original languageEnglish
Pages (from-to)98-103
Number of pages6
JournalJapanese Journal of Ophthalmology
Volume57
Issue number1
DOIs
Publication statusPublished - Jan 1 2013

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Acute Retinal Necrosis Syndrome
Vitrectomy
Visual Acuity
Observation
Retina
Odds Ratio
Retinal Detachment
Optic Nerve
Referral and Consultation
Logistic Models
Regression Analysis

All Science Journal Classification (ASJC) codes

  • Ophthalmology

Cite this

Iwahashi-Shima, C., Azumi, A., Ohguro, N., Okada, A. A., Kaburaki, T., Goto, H., ... Mochizuki, M. (2013). Acute retinal necrosis: Factors associated with anatomic and visual outcomes. Japanese Journal of Ophthalmology, 57(1), 98-103. https://doi.org/10.1007/s10384-012-0211-y

Acute retinal necrosis : Factors associated with anatomic and visual outcomes. / Iwahashi-Shima, Chiharu; Azumi, Atsushi; Ohguro, Nobuyuki; Okada, Annabelle A.; Kaburaki, Toshikatsu; Goto, Hiroshi; Sonoda, Kohei; Namba, Kenichi; Mizuki, Nobuhisa; Mochizuki, Manabu.

In: Japanese Journal of Ophthalmology, Vol. 57, No. 1, 01.01.2013, p. 98-103.

Research output: Contribution to journalArticle

Iwahashi-Shima, C, Azumi, A, Ohguro, N, Okada, AA, Kaburaki, T, Goto, H, Sonoda, K, Namba, K, Mizuki, N & Mochizuki, M 2013, 'Acute retinal necrosis: Factors associated with anatomic and visual outcomes', Japanese Journal of Ophthalmology, vol. 57, no. 1, pp. 98-103. https://doi.org/10.1007/s10384-012-0211-y
Iwahashi-Shima C, Azumi A, Ohguro N, Okada AA, Kaburaki T, Goto H et al. Acute retinal necrosis: Factors associated with anatomic and visual outcomes. Japanese Journal of Ophthalmology. 2013 Jan 1;57(1):98-103. https://doi.org/10.1007/s10384-012-0211-y
Iwahashi-Shima, Chiharu ; Azumi, Atsushi ; Ohguro, Nobuyuki ; Okada, Annabelle A. ; Kaburaki, Toshikatsu ; Goto, Hiroshi ; Sonoda, Kohei ; Namba, Kenichi ; Mizuki, Nobuhisa ; Mochizuki, Manabu. / Acute retinal necrosis : Factors associated with anatomic and visual outcomes. In: Japanese Journal of Ophthalmology. 2013 ; Vol. 57, No. 1. pp. 98-103.
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AU - Kaburaki, Toshikatsu

AU - Goto, Hiroshi

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