Adenoid cystic carcinoma of the lacrimal gland with wide and severe myoepithelial differentiation

Hiroyuki Mizokami, Akira Inokuchi, Motohiro Sawatsubashi, Seiji Takagi, Kuniyoshi Tsuda, Osamu Tokunaga

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Adenoid cystic carcinoma (ACC) of the lacrimal gland is the second most common epithelial tumor for which different biologic courses can be predicted by histologic criteria. Three main types of growth patterns, cribriform; tubular; and solid have been identified. Tumors with solid components frequently follow a more aggressive clinical course and show worse prognosis than those with other patterns. We herein report a case of ACC with wide and severe myoepithelial differentiation arising from the lacrimal gland and presenting with aggressive clinical behavior. Postoperative radiotherapy may be the treatment of choice to control residual lesions and provide long-term survival even in the case of incomplete resection. Despite extensive surgery and radiation therapy, the prognosis of these tumors, especially with solid components, remains extremely poor. Accurate diagnosis is important because tumor histopathology is generally believed to be the most significant factor in patient survival.

Original languageEnglish
Pages (from-to)77-82
Number of pages6
JournalAuris Nasus Larynx
Volume29
Issue number1
DOIs
Publication statusPublished - Jan 29 2002

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

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