Adenoma malignum of the uterine cervix detected by imaging methods in a patient with peutz-jeghers syndrome

Nobuhiro Tsuruchi, Naoki Tsukamoto, Tsunehisa Kaku, Toshiharu Kamura, Hitoo Nakano

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Adenoma malignum of the uterine cervix in a 25-year-old Japanese woman with Peutz-Jeghers syndrome (PJS) is described. A cervical multicystic mass was detected by CT scan, sonography, and MR imaging. These imaging findings strongly suggested the presence of adenoma malignum in spite of normal Pap smear, colposcopy, and cervical biopsy reports. Radical hysterectomy, bilateral salpingo-oophorectomy, pelvic lymphadenectomy, and para-aortic lymph node biopsy were performed after confirmation of adenoma malignum by conization. Both ovaries showed multicentric sex cord tumor with annular tubules. She is alive and well with no evidence of disease 23 months after surgery. Imaging methods including sonography, CT scan, and MR imaging may be useful aids in detecting the presence of adenoma malignum, especially in patients with PJS.

Original languageEnglish
Pages (from-to)232-236
Number of pages5
JournalGynecologic Oncology
Issue number2
Publication statusPublished - Jan 1 1994


All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

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