Adrenergic receptor signaling and regulation

Hitoshi Kurose

Adrenergic receptor signaling and regulation

Pharmaceutical Health Care and Sciences Faculty

Research output: Contribution to journal › Article

Abstract

At the beginning, β-arrestin is believed to regulate desensitization of G protein-coupled receptors. However, it becomes apparent that β-arrestin is involved in not only regulation but also signal transduction by identification of many proteins interacting with β-arrestin. So far, the model of regulation and signaling of G protein-coupled receptor is built on β₂-adrenergic receptor. However, this model does not apply to all G protein-coupled receptors. The differential regulation and signaling between β₁- and β₂-adrenergic receptors is presented.

Original language	English
Journal	Folia Pharmacologica Japonica
Volume	122
Issue number	SUPPL. 1
Publication status	Published - Dec 1 2003

All Science Journal Classification (ASJC) codes

Pharmacology

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Kurose, H. (2003). Adrenergic receptor signaling and regulation. Folia Pharmacologica Japonica, 122(SUPPL. 1).

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