Adrenergic receptor signaling and regulation

Research output: Contribution to journalArticle

Abstract

At the beginning, β-arrestin is believed to regulate desensitization of G protein-coupled receptors. However, it becomes apparent that β-arrestin is involved in not only regulation but also signal transduction by identification of many proteins interacting with β-arrestin. So far, the model of regulation and signaling of G protein-coupled receptor is built on β2-adrenergic receptor. However, this model does not apply to all G protein-coupled receptors. The differential regulation and signaling between β1- and β2-adrenergic receptors is presented.

Original languageEnglish
JournalFolia Pharmacologica Japonica
Volume122
Issue numberSUPPL. 1
Publication statusPublished - Dec 1 2003

All Science Journal Classification (ASJC) codes

  • Pharmacology

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