Advances in esophageal surgery in elderly patients with thoracic esophageal cancer

Masaru Morita, Hajime Otsu, Hiroyuki Kawano, Ryuichi Kumashiro, Kenji Taketani, Yasue Kimura, Hiroshi Saeki, Koji Ando, Satoshi Ida, Eiji Oki, Eriko Tokunaga, Tetsuo Ikeda, Tetsuya Kusumoto, Yoshihiko Maehara

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Aim: To justify esophagectomy for elderly patients. Patients and Methods: A total of 1,002 patients with thoracic esophageal cancer who underwent esophagectomy were divided into three groups: I (≤74 years old, n=898); II (75-79 years, n=81); and III (≥80 years, n=23). Historical changes were compared between the first surgical period (1964-1989) and the second period (1990-2011). Results: The morbidity rates were 40%, 41% and 26% in the respective groups. Pulmonary complications decreased historically in groups II and III (36% to 15% and 43% to 0%, respectively). The mortality was higher in the older groups (4.8%, 8.6% and 13.0%, respectively); however, there was a marked historical decrease in groups II (18.2% to 5.1%) and III (28.6% to 6.3%). The 5-year survival improved from 5% to 35% in group II and from 0% to 17% in group III. Conclusion: The outcomes of esophagectomy for elderly patients have markedly improved, with acceptable mortality even in octogenarians.

Original languageEnglish
Pages (from-to)1641-1648
Number of pages8
JournalAnticancer research
Volume33
Issue number4
Publication statusPublished - Apr 2013

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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    Morita, M., Otsu, H., Kawano, H., Kumashiro, R., Taketani, K., Kimura, Y., Saeki, H., Ando, K., Ida, S., Oki, E., Tokunaga, E., Ikeda, T., Kusumoto, T., & Maehara, Y. (2013). Advances in esophageal surgery in elderly patients with thoracic esophageal cancer. Anticancer research, 33(4), 1641-1648.