AFM observation of extracellular matrix adsorbed on thermosensitive polymer-films in water

Hiroshi Sunami, Naoko Ido, Masaru Tanaka, Sadaaki Yamamoto, Masatsugu Shimomura

Research output: Contribution to conferencePaperpeer-review

Abstract

Poly[2-(2-methoxyethoxy)ethyl methacrylate](PMEMA) with lower critical solution temperatures (LCST) of 22°C was prepared by free-radical polymerization of 2-(2-ethoxyethoxy)ethyl acrylate. The protein adsorption behavior was discussed by taking into account the changes in the surface properties of the polymer-films. There were much FBS proteins attached on the PMEMA films above the LCST compared to assays at lower temperature. Adsorption amounts of the proteins on the PMEMA films increased with increasing the temperature. These results showed that FBS protein adsorptions changed in surface properties governed by polymer transitions from hydrophilic to hydrophobic states.

Original languageEnglish
Number of pages1
Publication statusPublished - Dec 1 2005
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: May 25 2005May 27 2005

Other

Other54th SPSJ Annual Meeting 2005
CountryJapan
CityYokohama
Period5/25/055/27/05

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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