TY - JOUR
T1 - Age estimation in dental pulp DNA based on human telomere shortening
AU - Takasaki, Tomoya
AU - Tsuji, Akiko
AU - Ikeda, Noriaki
AU - Ohishi, Masamichi
PY - 2003/8
Y1 - 2003/8
N2 - Age estimation based on evidence found in teeth has received considerable attention within the field of forensic science. We determined the terminal restriction fragment (TRF) length, as telomere length, to estimate age. Using dental pulp DNA we found the average TRF length showed a tendency to shortening with aging. Our findings show that telomere shortening, based on dental pulp DNA is a new and useful approach to estimate age of the subject at the time of death.
AB - Age estimation based on evidence found in teeth has received considerable attention within the field of forensic science. We determined the terminal restriction fragment (TRF) length, as telomere length, to estimate age. Using dental pulp DNA we found the average TRF length showed a tendency to shortening with aging. Our findings show that telomere shortening, based on dental pulp DNA is a new and useful approach to estimate age of the subject at the time of death.
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U2 - 10.1007/s00414-003-0376-5
DO - 10.1007/s00414-003-0376-5
M3 - Article
C2 - 12838429
AN - SCOPUS:0042930915
SN - 0937-9827
VL - 117
SP - 232
EP - 234
JO - Zeitschrift fur Rechtsmedizin. Journal of legal medicine
JF - Zeitschrift fur Rechtsmedizin. Journal of legal medicine
IS - 4
ER -