TY - JOUR
T1 - Age-related changes in pattern visual evoked potentials
T2 - differential effects of luminance, contrast and check size
AU - Tobimatsu, Shozo
AU - Kurita-Tashima, Shizuka
AU - Nakayama-Hiromatsu, Miyuki
AU - Akazawa, Kohei
AU - Kato, Motohiro
PY - 1993/1/1
Y1 - 1993/1/1
N2 - We recorded visual evoked potentials (VEPs) to checkerboard pattern-reversal stimulation in 109 normal subjects (51 males and 59 females; aged 19-84 years) in order to study the aging effect on the multiple channels of the visual system in humans. Transient VEPs to 3 check sizes (15′, 30′ and 50′) were obtained by monocular stimulation. Two test conditions were employed: (1) a high luminance (180 cd/m2) and a low luminance (11 cd/m2) both with a fixed contrast (90%), and (2) a high contrast (85%) and a low contrast (10%) both at a fixed luminance (57 cd/m2). The major features of our results included: (1) the presence of a curvilinear relationship between P100 latency and age for all conditions, while the P100 amplitude did not show any such aging effect, (2) the age-latency function was similar between the two luminance conditions, while it was different between the two contrast conditions, and (3) the differential age effect on the P100 latency caused by changes in contrast depended on the check size. These results suggest that age-related changes in the human visual system are not uniform, but rather are different in the specific functional subdivisions. It is thus hypothesized that aging may differentially influence the separate channels of the human visual system.
AB - We recorded visual evoked potentials (VEPs) to checkerboard pattern-reversal stimulation in 109 normal subjects (51 males and 59 females; aged 19-84 years) in order to study the aging effect on the multiple channels of the visual system in humans. Transient VEPs to 3 check sizes (15′, 30′ and 50′) were obtained by monocular stimulation. Two test conditions were employed: (1) a high luminance (180 cd/m2) and a low luminance (11 cd/m2) both with a fixed contrast (90%), and (2) a high contrast (85%) and a low contrast (10%) both at a fixed luminance (57 cd/m2). The major features of our results included: (1) the presence of a curvilinear relationship between P100 latency and age for all conditions, while the P100 amplitude did not show any such aging effect, (2) the age-latency function was similar between the two luminance conditions, while it was different between the two contrast conditions, and (3) the differential age effect on the P100 latency caused by changes in contrast depended on the check size. These results suggest that age-related changes in the human visual system are not uniform, but rather are different in the specific functional subdivisions. It is thus hypothesized that aging may differentially influence the separate channels of the human visual system.
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U2 - 10.1016/0168-5597(93)90023-I
DO - 10.1016/0168-5597(93)90023-I
M3 - Article
C2 - 7681386
AN - SCOPUS:0027163995
VL - 88
SP - 12
EP - 19
JO - Electroencephalography and Clinical Neurophysiology - Evoked Potentials
JF - Electroencephalography and Clinical Neurophysiology - Evoked Potentials
SN - 0168-5597
IS - 1
ER -