Aggregation behavior and reactivity of hydrophobic vitamin B12 covalently bound to lipid in aqueous media

Yukito Murakami; Yoshio Hisaeda; Akihiro Ogawa; Tetsuya Miyajima; Osamu Hayashida; Teruhisa Ohno

doi:10.1016/0040-4039(93)89033-M

Aggregation behavior and reactivity of hydrophobic vitamin B₁₂ covalently bound to lipid in aqueous media

Yukito Murakami, Yoshio Hisaeda, Akihiro Ogawa, Tetsuya Miyajima, Osamu Hayashida, Teruhisa Ohno

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

A mixture of a hydrophobic vitamin B₁₂ covalently bound to a lipid species and N,N-dihexadecyl-N^α- [6-(trimethylammonio)hexanoyl]-L-alaninamide bromide at a 1 : 50 molar ratio afforded stable single-compartment vesicles by sonication, which provided an anaerobic microenvironment in aqueous media under aerobic conditions.

Original language	English
Pages (from-to)	863-866
Number of pages	4
Journal	Tetrahedron Letters
Volume	34
Issue number	5
DOIs	https://doi.org/10.1016/0040-4039(93)89033-M
Publication status	Published - Jan 29 1993

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/0040-4039(93)89033-M

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abstract = "A mixture of a hydrophobic vitamin B12 covalently bound to a lipid species and N,N-dihexadecyl-Nα- [6-(trimethylammonio)hexanoyl]-L-alaninamide bromide at a 1 : 50 molar ratio afforded stable single-compartment vesicles by sonication, which provided an anaerobic microenvironment in aqueous media under aerobic conditions.",

author = "Yukito Murakami and Yoshio Hisaeda and Akihiro Ogawa and Tetsuya Miyajima and Osamu Hayashida and Teruhisa Ohno",

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T1 - Aggregation behavior and reactivity of hydrophobic vitamin B12 covalently bound to lipid in aqueous media

AU - Murakami, Yukito

AU - Hisaeda, Yoshio

AU - Ogawa, Akihiro

AU - Miyajima, Tetsuya

AU - Hayashida, Osamu

AU - Ohno, Teruhisa

PY - 1993/1/29

Y1 - 1993/1/29

N2 - A mixture of a hydrophobic vitamin B12 covalently bound to a lipid species and N,N-dihexadecyl-Nα- [6-(trimethylammonio)hexanoyl]-L-alaninamide bromide at a 1 : 50 molar ratio afforded stable single-compartment vesicles by sonication, which provided an anaerobic microenvironment in aqueous media under aerobic conditions.

AB - A mixture of a hydrophobic vitamin B12 covalently bound to a lipid species and N,N-dihexadecyl-Nα- [6-(trimethylammonio)hexanoyl]-L-alaninamide bromide at a 1 : 50 molar ratio afforded stable single-compartment vesicles by sonication, which provided an anaerobic microenvironment in aqueous media under aerobic conditions.

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ER -

Aggregation behavior and reactivity of hydrophobic vitamin B₁₂ covalently bound to lipid in aqueous media

Abstract

All Science Journal Classification (ASJC) codes

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