Aggregation behavior and reactivity of hydrophobic vitamin B12 covalently bound to lipid in aqueous media

Yukito Murakami, Yoshio Hisaeda, Akihiro Ogawa, Tetsuya Miyajima, Osamu Hayashida, Teruhisa Ohno

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

A mixture of a hydrophobic vitamin B12 covalently bound to a lipid species and N,N-dihexadecyl-Nα- [6-(trimethylammonio)hexanoyl]-L-alaninamide bromide at a 1 : 50 molar ratio afforded stable single-compartment vesicles by sonication, which provided an anaerobic microenvironment in aqueous media under aerobic conditions.

Original languageEnglish
Pages (from-to)863-866
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number5
DOIs
Publication statusPublished - Jan 29 1993

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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