水界面におけるバイオイナート高分子の凝集状態と熱運動特性

Translated title of the contribution: Aggregation state and thermal molecular motion of a bio-inert polymer at the water interface

    Research output: Contribution to journalArticlepeer-review

    Abstract

    In this study, we prepared stable and flat surfaces of poly(2-methoxyethyl acrylate) (PMEA) which exhibit excellent bio-inert properties in a thin film state by blending it with poly(methyl methacrylate) (PMMA) and annealing at an appropriate temperature, higher than the glass transition temperature and lower than the phase-separation temperature of the blend. Furthermore, the aggregation state and thermal molecular motion of PMEA at the water interface were examined. After contacting with water, PMEA segregated to the water interface in the blend film. While the local conformation of PMEA at the water interface was insensitive to its molecular weight, the local dynamics became faster with decreasing molecular weight, resulting in a disturbance of the network structure of water molecules at the interface. This leads to the extreme suppression of protein adsorption and platelet adhesion.

    Translated title of the contributionAggregation state and thermal molecular motion of a bio-inert polymer at the water interface
    Original languageJapanese
    Pages (from-to)185-195
    Number of pages11
    JournalKOBUNSHI RONBUNSHU
    Volume76
    Issue number3
    DOIs
    Publication statusPublished - 2019

    All Science Journal Classification (ASJC) codes

    • Chemical Engineering (miscellaneous)
    • Materials Science (miscellaneous)
    • Environmental Science(all)
    • Polymers and Plastics

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