Aggregation structure of DNA-conjugated gold nanoparticles

Shizuto Yamakoshi, Yasuhiro Sakai, Kohzo Ito, Yuuya Shinohara, Yoshiyuki Amemiya, Naoki Kanayama, Tohru Takarada, Mizuo Maeda

Research output: Chapter in Book/Report/Conference proceedingConference contribution


DNA-conjugated gold nanoparticles exhibit a unique aggregation behavior that they form aggregation with fully complementary DNA but do not with the terminal-mismatched DNA at certain concentration of added salts. We studied the aggregation structure of the nanoparticles by small angle X-ray scattering (SAXS). The results indicated that the gap between surfaces of gold nanoparticles is nearly two times as long as DNA in B-form.This suggests that the ends of completely double-strand DNA conjugated on gold nanoparticles contact or interdigitate slightly with each other in the aggeregation structure.

Original languageEnglish
Title of host publicationPolymer Preprints, Japan - 55th SPSJ Annual Meeting
Number of pages1
Publication statusPublished - 2006
Externally publishedYes
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: May 24 2006May 26 2006


Other55th SPSJ Annual Meeting

All Science Journal Classification (ASJC) codes

  • Engineering(all)

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  • Cite this

    Yamakoshi, S., Sakai, Y., Ito, K., Shinohara, Y., Amemiya, Y., Kanayama, N., Takarada, T., & Maeda, M. (2006). Aggregation structure of DNA-conjugated gold nanoparticles. In Polymer Preprints, Japan - 55th SPSJ Annual Meeting (1 ed., Vol. 55, pp. 2178)