Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp.

Akiko Fukami, Yoko Ikeda, Shinichi Kondo, Hiroshi Naganawa, Tomio Takeuchi, Shigeki Furuya, Yoshio Hirabayashi, Kazuyuki Shimoike, Saburo Hosaka, Yoko Watanabe, Kazuo Umezawa

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Akaterpin (1), an inhibitor of phosphatidylinositol-specific phospholipase C, was isolated from an acetone extract of the marine sponge, Callyspongia sp. Structural determination by 2D-NMR spectroscopy revealed that it was a novel triterpene with the hydroquinone disulfate.

Original languageEnglish
Pages (from-to)1201-1202
Number of pages2
JournalTetrahedron Letters
Volume38
Issue number7
DOIs
Publication statusPublished - Feb 17 1997
Externally publishedYes

Fingerprint

Callyspongia
Phosphoinositide Phospholipase C
Triterpenes
Porifera
Acetone
Nuclear magnetic resonance spectroscopy
Magnetic Resonance Spectroscopy
akaterpin
hydroquinone

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Fukami, A., Ikeda, Y., Kondo, S., Naganawa, H., Takeuchi, T., Furuya, S., ... Umezawa, K. (1997). Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp. Tetrahedron Letters, 38(7), 1201-1202. https://doi.org/10.1016/S0040-4039(97)00016-6

Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp. / Fukami, Akiko; Ikeda, Yoko; Kondo, Shinichi; Naganawa, Hiroshi; Takeuchi, Tomio; Furuya, Shigeki; Hirabayashi, Yoshio; Shimoike, Kazuyuki; Hosaka, Saburo; Watanabe, Yoko; Umezawa, Kazuo.

In: Tetrahedron Letters, Vol. 38, No. 7, 17.02.1997, p. 1201-1202.

Research output: Contribution to journalArticle

Fukami, A, Ikeda, Y, Kondo, S, Naganawa, H, Takeuchi, T, Furuya, S, Hirabayashi, Y, Shimoike, K, Hosaka, S, Watanabe, Y & Umezawa, K 1997, 'Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp.', Tetrahedron Letters, vol. 38, no. 7, pp. 1201-1202. https://doi.org/10.1016/S0040-4039(97)00016-6
Fukami, Akiko ; Ikeda, Yoko ; Kondo, Shinichi ; Naganawa, Hiroshi ; Takeuchi, Tomio ; Furuya, Shigeki ; Hirabayashi, Yoshio ; Shimoike, Kazuyuki ; Hosaka, Saburo ; Watanabe, Yoko ; Umezawa, Kazuo. / Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp. In: Tetrahedron Letters. 1997 ; Vol. 38, No. 7. pp. 1201-1202.
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