Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp.

Akiko Fukami; Yoko Ikeda; Shinichi Kondo; Hiroshi Naganawa; Tomio Takeuchi; Shigeki Furuya; Yoshio Hirabayashi; Kazuyuki Shimoike; Saburo Hosaka; Yoko Watanabe; Kazuo Umezawa

doi:10.1016/S0040-4039(97)00016-6

Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp.

Akiko Fukami, Yoko Ikeda, Shinichi Kondo, Hiroshi Naganawa, Tomio Takeuchi, Shigeki Furuya, Yoshio Hirabayashi, Kazuyuki Shimoike, Saburo Hosaka, Yoko Watanabe, Kazuo Umezawa

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

Akaterpin (1), an inhibitor of phosphatidylinositol-specific phospholipase C, was isolated from an acetone extract of the marine sponge, Callyspongia sp. Structural determination by 2D-NMR spectroscopy revealed that it was a novel triterpene with the hydroquinone disulfate.

Original language	English
Pages (from-to)	1201-1202
Number of pages	2
Journal	Tetrahedron Letters
Volume	38
Issue number	7
DOIs	https://doi.org/10.1016/S0040-4039(97)00016-6
Publication status	Published - Feb 17 1997
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0040-4039(97)00016-6

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title = "Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp.",

abstract = "Akaterpin (1), an inhibitor of phosphatidylinositol-specific phospholipase C, was isolated from an acetone extract of the marine sponge, Callyspongia sp. Structural determination by 2D-NMR spectroscopy revealed that it was a novel triterpene with the hydroquinone disulfate.",

author = "Akiko Fukami and Yoko Ikeda and Shinichi Kondo and Hiroshi Naganawa and Tomio Takeuchi and Shigeki Furuya and Yoshio Hirabayashi and Kazuyuki Shimoike and Saburo Hosaka and Yoko Watanabe and Kazuo Umezawa",

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T1 - Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp.

AU - Fukami, Akiko

AU - Ikeda, Yoko

AU - Kondo, Shinichi

AU - Naganawa, Hiroshi

AU - Takeuchi, Tomio

AU - Furuya, Shigeki

AU - Hirabayashi, Yoshio

AU - Shimoike, Kazuyuki

AU - Hosaka, Saburo

AU - Watanabe, Yoko

AU - Umezawa, Kazuo

PY - 1997/2/17

Y1 - 1997/2/17

N2 - Akaterpin (1), an inhibitor of phosphatidylinositol-specific phospholipase C, was isolated from an acetone extract of the marine sponge, Callyspongia sp. Structural determination by 2D-NMR spectroscopy revealed that it was a novel triterpene with the hydroquinone disulfate.

AB - Akaterpin (1), an inhibitor of phosphatidylinositol-specific phospholipase C, was isolated from an acetone extract of the marine sponge, Callyspongia sp. Structural determination by 2D-NMR spectroscopy revealed that it was a novel triterpene with the hydroquinone disulfate.

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U2 - 10.1016/S0040-4039(97)00016-6

DO - 10.1016/S0040-4039(97)00016-6

M3 - Article

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SN - 0040-4039

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 7

ER -

Akaterpin, a novel bioactive triterpene from the marine sponge Callyspongia sp.

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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