Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope

Masato Tsutsui, Takeyuki Matsuguchi, Hiroyuki Tsutsui, Shingo Yoshihara, Kunihiko Yamamoto, Hiroaki Shimokawa, Shuichi Okamatsu, Ryuichi Hisanou, Tetsuhiko Yoshida

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We observed 2 cases of repeated episodes of syncope after alcohol ingestion. Both patients were light drinkers and had carotid sinus hypersensitivity. In both cases, alcohol loading tests repeatedly induced sinus bradycardia and hypotension 1.0-1.5 hours after drinking alcohol. Atropine was effective in improving symptoms. A loading test using a glucose solution of equivalent osmolarity and volume was negative. Acute alcohol ingestion usually increases heart rate with variable effects on blood pressure. However, our 2 cases exhibited unusual alcohol-induced sinus bradycardia and hypotension, suggesting a paradoxical increase in parasympathetic activity and/or decrease in sympathetic activity.

Original languageEnglish
Pages (from-to)875-879
Number of pages5
Journaljapanese heart journal
Volume33
Issue number6
DOIs
Publication statusPublished - Jan 1 1992
Externally publishedYes

Fingerprint

Syncope
Bradycardia
Hypotension
Alcohols
Eating
Carotid Sinus
Atropine
Alcohol Drinking
Osmolar Concentration
Hypersensitivity
Heart Rate
Blood Pressure
Glucose

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Tsutsui, M., Matsuguchi, T., Tsutsui, H., Yoshihara, S., Yamamoto, K., Shimokawa, H., ... Yoshida, T. (1992). Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope. japanese heart journal, 33(6), 875-879. https://doi.org/10.1536/ihj.33.875

Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope. / Tsutsui, Masato; Matsuguchi, Takeyuki; Tsutsui, Hiroyuki; Yoshihara, Shingo; Yamamoto, Kunihiko; Shimokawa, Hiroaki; Okamatsu, Shuichi; Hisanou, Ryuichi; Yoshida, Tetsuhiko.

In: japanese heart journal, Vol. 33, No. 6, 01.01.1992, p. 875-879.

Research output: Contribution to journalArticle

Tsutsui, M, Matsuguchi, T, Tsutsui, H, Yoshihara, S, Yamamoto, K, Shimokawa, H, Okamatsu, S, Hisanou, R & Yoshida, T 1992, 'Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope', japanese heart journal, vol. 33, no. 6, pp. 875-879. https://doi.org/10.1536/ihj.33.875
Tsutsui M, Matsuguchi T, Tsutsui H, Yoshihara S, Yamamoto K, Shimokawa H et al. Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope. japanese heart journal. 1992 Jan 1;33(6):875-879. https://doi.org/10.1536/ihj.33.875
Tsutsui, Masato ; Matsuguchi, Takeyuki ; Tsutsui, Hiroyuki ; Yoshihara, Shingo ; Yamamoto, Kunihiko ; Shimokawa, Hiroaki ; Okamatsu, Shuichi ; Hisanou, Ryuichi ; Yoshida, Tetsuhiko. / Alcohol-Induced Sinus Bradycardia and Hypotension in Patients with Syncope. In: japanese heart journal. 1992 ; Vol. 33, No. 6. pp. 875-879.
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