Alkylcobyrinate from sucralose and mechanistic aspects of its CoC bond cleavage

Hitesh V. Motwani, Hisashi Shimakoshi, Bernard T. Golding, Margareta Törnqvist, Yoshio Hisaeda

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Reaction of heptamethyl cob(I)yrinate with 1′,6′-dichloro- 1′,6′-dideoxy-β-d-fructofuranosyl-4-chloro-4-deoxy-α-d- galactopyranoside (sucralose) gave an alkylcobyrinate, heptamethyl-6′- [α-d-galactopyranoside- 1′-chloro-1′,6′-dideoxy-β- d-fructofuranosyl-4-chloro-4-deoxy]cobyrinate perchlorate, [(Suc)Cob(III)7C 1ester]ClO4. Cleavage behavior of CoC bond of the alkylcobyrinate was investigated under various conditions (hν, H+ and reduction) using UV-vis spectroscopy combined with the EPR spin-trapping technique, and by cyclic voltammetry.

Original languageEnglish
Pages (from-to)2667-2670
Number of pages4
JournalTetrahedron Letters
Volume55
Issue number16
DOIs
Publication statusPublished - Apr 16 2014

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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