Allergic tendencies are associated with larger gray matter volumes

Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Ryoichi Yokoyama, Yuka Kotozaki, Seishu Nakagawa, Atsushi Sekiguchi, Kunio Iizuka, Yuki Yamamoto, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Kohei Sakaki, Takayuki Nozawa, Shigeyuki Ikeda, Susumu Yokota, Magistro Daniele, Yuko Sassa, Ryuta Kawashima

Research output: Contribution to journalArticle

Abstract

Allergic tendencies are associated with important cognitive and physiological factors, such as intelligence and mathematical abilities. Allergies are widely prevalent, especially in modern life, and the reason for its association with important cognitive variables is an intriguing scientific question. However, despite the unique characteristics of cognitive correlates of allergy, the anatomical correlates of allergy remain unknown. The aim of this study was to identify the associations between regional gray matter volume (rGMV) and allergic tendencies in young adults. In a study cohort of 1,219 healthy, educated young adults, we identified a positive correlation between total allergic tendency and rGMV in large anatomical clusters that mainly encompassed the dorsal part of the cerebral neocortex, right anterior insula, and cerebellum. Furthermore, both mean rGMV of the entire part of these clusters and total allergenic tendency showed a significant positive correlation with spatial ability. These results suggest the link among allergic tendencies, larger rGMV, and the better spatial ability in healthy, educated young adults.

Original languageEnglish
Article number3694
JournalScientific reports
Volume8
Issue number1
DOIs
Publication statusPublished - Dec 1 2018
Externally publishedYes

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Young Adult
Hypersensitivity
Aptitude
Neocortex
Intelligence
Cerebellum
Cohort Studies
Gray Matter
Spatial Navigation

All Science Journal Classification (ASJC) codes

  • General

Cite this

Takeuchi, H., Taki, Y., Nouchi, R., Yokoyama, R., Kotozaki, Y., Nakagawa, S., ... Kawashima, R. (2018). Allergic tendencies are associated with larger gray matter volumes. Scientific reports, 8(1), [3694]. https://doi.org/10.1038/s41598-018-21985-8

Allergic tendencies are associated with larger gray matter volumes. / Takeuchi, Hikaru; Taki, Yasuyuki; Nouchi, Rui; Yokoyama, Ryoichi; Kotozaki, Yuka; Nakagawa, Seishu; Sekiguchi, Atsushi; Iizuka, Kunio; Yamamoto, Yuki; Hanawa, Sugiko; Araki, Tsuyoshi; Miyauchi, Carlos Makoto; Sakaki, Kohei; Nozawa, Takayuki; Ikeda, Shigeyuki; Yokota, Susumu; Daniele, Magistro; Sassa, Yuko; Kawashima, Ryuta.

In: Scientific reports, Vol. 8, No. 1, 3694, 01.12.2018.

Research output: Contribution to journalArticle

Takeuchi, H, Taki, Y, Nouchi, R, Yokoyama, R, Kotozaki, Y, Nakagawa, S, Sekiguchi, A, Iizuka, K, Yamamoto, Y, Hanawa, S, Araki, T, Miyauchi, CM, Sakaki, K, Nozawa, T, Ikeda, S, Yokota, S, Daniele, M, Sassa, Y & Kawashima, R 2018, 'Allergic tendencies are associated with larger gray matter volumes', Scientific reports, vol. 8, no. 1, 3694. https://doi.org/10.1038/s41598-018-21985-8
Takeuchi H, Taki Y, Nouchi R, Yokoyama R, Kotozaki Y, Nakagawa S et al. Allergic tendencies are associated with larger gray matter volumes. Scientific reports. 2018 Dec 1;8(1). 3694. https://doi.org/10.1038/s41598-018-21985-8
Takeuchi, Hikaru ; Taki, Yasuyuki ; Nouchi, Rui ; Yokoyama, Ryoichi ; Kotozaki, Yuka ; Nakagawa, Seishu ; Sekiguchi, Atsushi ; Iizuka, Kunio ; Yamamoto, Yuki ; Hanawa, Sugiko ; Araki, Tsuyoshi ; Miyauchi, Carlos Makoto ; Sakaki, Kohei ; Nozawa, Takayuki ; Ikeda, Shigeyuki ; Yokota, Susumu ; Daniele, Magistro ; Sassa, Yuko ; Kawashima, Ryuta. / Allergic tendencies are associated with larger gray matter volumes. In: Scientific reports. 2018 ; Vol. 8, No. 1.
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