Allogeneic haematopoietic cell transplantation for adult acute myeloid leukaemia in second remission: a retrospective study of the Adult Acute Myeloid Leukaemia Working Group of the Japan Society for Haematopoietic Cell Transplantation (JSHCT)

Takaaki Konuma, Masamitsu Yanada, Satoshi Yamasaki, Yachiyo Kuwatsuka, Takahiro Fukuda, Takeshi Kobayashi, Yukiyasu Ozawa, Naoyuki Uchida, Shuichi Ota, Takumi Hoshino, Satoshi Takahashi, Yoshinobu Kanda, Yasunori Ueda, Minoko Takanashi, Junya Kanda, Tatsuo Ichinohe, Yoshiko Atsuta, Shingo Yano

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

To evaluate the outcomes and prognostic factors following allogeneic haematopoietic cell transplantation (HCT) for adult acute myeloid leukaemia (AML) in second complete remission (CR2), we retrospectively analysed the Japanese registration data of 1080 adult AML patients in CR2 who had received allogeneic HCT. The probability of overall survival and the cumulative incidence of relapse at 3 years was 66% and 19%, respectively. In multivariate analysis, older age, poor cytogenetics and shorter duration of first complete remission were significantly associated with a higher overall mortality. Our data demonstrated the significant efficacy of allogeneic HCT for adult AML in CR2.

Original languageEnglish
Pages (from-to)245-250
Number of pages6
JournalBritish Journal of Haematology
Volume182
Issue number2
DOIs
Publication statusPublished - Jul 2018
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Hematology

Fingerprint

Dive into the research topics of 'Allogeneic haematopoietic cell transplantation for adult acute myeloid leukaemia in second remission: a retrospective study of the Adult Acute Myeloid Leukaemia Working Group of the Japan Society for Haematopoietic Cell Transplantation (JSHCT)'. Together they form a unique fingerprint.

Cite this