@article{5b14fde662494452bfb6631ba64bd1f3,
title = "Allogeneic haematopoietic cell transplantation for adult acute myeloid leukaemia in second remission: a retrospective study of the Adult Acute Myeloid Leukaemia Working Group of the Japan Society for Haematopoietic Cell Transplantation (JSHCT)",
abstract = "To evaluate the outcomes and prognostic factors following allogeneic haematopoietic cell transplantation (HCT) for adult acute myeloid leukaemia (AML) in second complete remission (CR2), we retrospectively analysed the Japanese registration data of 1080 adult AML patients in CR2 who had received allogeneic HCT. The probability of overall survival and the cumulative incidence of relapse at 3 years was 66% and 19%, respectively. In multivariate analysis, older age, poor cytogenetics and shorter duration of first complete remission were significantly associated with a higher overall mortality. Our data demonstrated the significant efficacy of allogeneic HCT for adult AML in CR2.",
author = "Takaaki Konuma and Masamitsu Yanada and Satoshi Yamasaki and Yachiyo Kuwatsuka and Takahiro Fukuda and Takeshi Kobayashi and Yukiyasu Ozawa and Naoyuki Uchida and Shuichi Ota and Takumi Hoshino and Satoshi Takahashi and Yoshinobu Kanda and Yasunori Ueda and Minoko Takanashi and Junya Kanda and Tatsuo Ichinohe and Yoshiko Atsuta and Shingo Yano",
note = "Funding Information: 1Department of Haematology/Oncology, The Institute of Medical Science, The University of Tokyo, Tokyo, 2Department of Haematology, Fujita Health University School of Medicine, Toyoake, 3Department of Haematology and Clinical Research Institute, National Hospital Organization Kyushu Medical Centre, Fukuoka, 4Centre for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, 5Department of Haematopoietic Stem Cell Transplantation, National Cancer Centre Hospital, 6Haematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Centre, Koma-gome Hospital, Tokyo, 7Department of Haematology, Japanese Red Cross Nagoya First Hospital, Nagoya, 8Department of Haematology, Federation of National Public Service Personnel Mutual Aid Associations Toranomon Hospital, Tokyo, 9Department of Haematology, Sapporo Hokuyu Hospital, Sapporo, 10Leukaemia Research Centre, Saiseikai Maebashi Hospital, Maebashi, 11Division of Molecular Therapy, The Advanced Clinical Research Centre, The Institute of Medical Science, The University of Tokyo, Tokyo, 12Division of Haematology, Saitama Medical Centr, Jichi Medical University, Saitama, 13Department of Haematology and Oncology, Kurashiki Central Hospital, Kurashiki, 14Blood Service Headquarters, Japanese Red Cross Society, Tokyo, 15Department of Haematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, 16Department of Funding Information: We thank all of the physicians and staff at the centres who provided the clinical data to the Transplant Registry Unified Management Program (TRUMP) of the Japan Society of Haematopoietic Cell Transplantation (JSHCT). Publisher Copyright: {\textcopyright} 2018 John Wiley & Sons Ltd",
year = "2018",
month = jul,
doi = "10.1111/bjh.15399",
language = "English",
volume = "182",
pages = "245--250",
journal = "British Journal of Haematology",
issn = "0007-1048",
publisher = "Wiley-Blackwell",
number = "2",
}