TY - JOUR
T1 - Alteration of proton diffusivity associated with passive muscle extension and contraction
AU - Hatakenaka, Masamitsu
AU - Matsuo, Yoshio
AU - Setoguchi, Taro
AU - Yabuuchi, Hidetake
AU - Okafuji, Takashi
AU - Kamitani, Takeshi
AU - Nishikawa, Kei
AU - Honda, Hiroshi
PY - 2008/4
Y1 - 2008/4
N2 - Purpose: To determine whether passive muscle extension and contraction affect the proton diffusivity of the muscle. Materials and Methods: Five male subjects were examined. The fractional anisotropy (FA), and primary (λ1), secondary (λ2), and tertiary eigenvalues (λ3) of the right tibialis anterior and medial gastrocnemius muscles were compared between conditions of passive plantar flexion and passive dorsiflexion of the ankle joint. Results: In the tibialis anterior, FA, and λ1 at dorsiflexion decreased significantly (P < 0.01 and P < 0.01, respectively) compared to those at plantar flexion, but λ3 at dorsiflexion increased significantly (P = 0.02). In the gastrocnemius, FA and λ1 at dorsiflexion increased significantly (P < 0.01 and P < 0.01, respectively) compared to those at plantar flexion, but λ3 at dorsiflexion decreased significantly (P < 0.01). The λ2 value showed no significant change in either the tibialis anterior or medial gastrocnemius. Conclusion: The results indicate that passive muscle extension and contraction associated with passive joint movement would affect the proton diffusivity of the muscle. This alteration of proton diffusivity is probably associated with microscopic structural changes of the muscle.
AB - Purpose: To determine whether passive muscle extension and contraction affect the proton diffusivity of the muscle. Materials and Methods: Five male subjects were examined. The fractional anisotropy (FA), and primary (λ1), secondary (λ2), and tertiary eigenvalues (λ3) of the right tibialis anterior and medial gastrocnemius muscles were compared between conditions of passive plantar flexion and passive dorsiflexion of the ankle joint. Results: In the tibialis anterior, FA, and λ1 at dorsiflexion decreased significantly (P < 0.01 and P < 0.01, respectively) compared to those at plantar flexion, but λ3 at dorsiflexion increased significantly (P = 0.02). In the gastrocnemius, FA and λ1 at dorsiflexion increased significantly (P < 0.01 and P < 0.01, respectively) compared to those at plantar flexion, but λ3 at dorsiflexion decreased significantly (P < 0.01). The λ2 value showed no significant change in either the tibialis anterior or medial gastrocnemius. Conclusion: The results indicate that passive muscle extension and contraction associated with passive joint movement would affect the proton diffusivity of the muscle. This alteration of proton diffusivity is probably associated with microscopic structural changes of the muscle.
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U2 - 10.1002/jmri.21302
DO - 10.1002/jmri.21302
M3 - Article
C2 - 18383254
AN - SCOPUS:41949099761
SN - 1053-1807
VL - 27
SP - 932
EP - 937
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
IS - 4
ER -