Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine

T. Tsuchihashi, A. Tsukashima, K. Matsumura, I. Abe, M. Tominaga, Y. Nakao, K. Kobayashi, M. Fujishima

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Abstract

A newly developed calcium antagonist, nilvadipine, was administered to 7 hypertensive patients aged 75.6 y. Nilvadipine 4 mg b.d. decreased the average 24-h blood pressure significantly from 169/89 mm Hg to 152/81 mm Hg after 7 to 14 days without any change in the pulse rate. The circadian patterns of blood pressure and pulse rate were not affected by nilvadipine. Although the present study was a preliminary one done over a short period in a small number of patients, the results suggest that nilvadipine exerts an antihypertensive effect without altering the circadian pattern or the variability of blood pressure in elderly hypertensive patients.

Original languageEnglish
Pages (from-to)255-257
Number of pages3
JournalEuropean Journal of Clinical Pharmacology
Volume41
Issue number3
DOIs
Publication statusPublished - Sep 1 1991

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)

Cite this

Tsuchihashi, T., Tsukashima, A., Matsumura, K., Abe, I., Tominaga, M., Nakao, Y., ... Fujishima, M. (1991). Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine. European Journal of Clinical Pharmacology, 41(3), 255-257. https://doi.org/10.1007/BF00315439