An amphiphilic fluorescent probe for the visualization of histamine in living cells

Daisuke Seto, Nobuaki Soh, Koji Nakano, Toshihiko Imato

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A novel fluorescent probe composed of two moieties, Nile Red and an iminodiacetic acid-Ni2+ complex, for the detection of histamine in living cells is described. The probe was successfully applied to visualizing histamine in RAW264 cells, representing the first demonstration of the imaging of histamine itself in living cells.

Original languageEnglish
Pages (from-to)6708-6711
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume20
Issue number22
DOIs
Publication statusPublished - Nov 15 2010

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Fluorescent Dyes
Histamine
Visualization
Cells
Demonstrations
Imaging techniques

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Cite this

An amphiphilic fluorescent probe for the visualization of histamine in living cells. / Seto, Daisuke; Soh, Nobuaki; Nakano, Koji; Imato, Toshihiko.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 20, No. 22, 15.11.2010, p. 6708-6711.

Research output: Contribution to journalArticle

Seto, Daisuke ; Soh, Nobuaki ; Nakano, Koji ; Imato, Toshihiko. / An amphiphilic fluorescent probe for the visualization of histamine in living cells. In: Bioorganic and Medicinal Chemistry Letters. 2010 ; Vol. 20, No. 22. pp. 6708-6711.
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