An amphiphilic fluorescent probe for the visualization of histamine in living cells

Daisuke Seto, Nobuaki Soh, Koji Nakano, Toshihiko Imato

    Research output: Contribution to journalArticlepeer-review

    23 Citations (Scopus)

    Abstract

    A novel fluorescent probe composed of two moieties, Nile Red and an iminodiacetic acid-Ni2+ complex, for the detection of histamine in living cells is described. The probe was successfully applied to visualizing histamine in RAW264 cells, representing the first demonstration of the imaging of histamine itself in living cells.

    Original languageEnglish
    Pages (from-to)6708-6711
    Number of pages4
    JournalBioorganic and Medicinal Chemistry Letters
    Volume20
    Issue number22
    DOIs
    Publication statusPublished - Nov 15 2010

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Molecular Medicine
    • Molecular Biology
    • Pharmaceutical Science
    • Drug Discovery
    • Clinical Biochemistry
    • Organic Chemistry

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