An amphiphilic fluorescent probe for the visualization of histamine in living cells

Daisuke Seto; Nobuaki Soh; Koji Nakano; Toshihiko Imato

doi:10.1016/j.bmcl.2010.09.003

An amphiphilic fluorescent probe for the visualization of histamine in living cells

Daisuke Seto, Nobuaki Soh, Koji Nakano, Toshihiko Imato

Molecular Information Chemistry

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

A novel fluorescent probe composed of two moieties, Nile Red and an iminodiacetic acid-Ni²⁺ complex, for the detection of histamine in living cells is described. The probe was successfully applied to visualizing histamine in RAW264 cells, representing the first demonstration of the imaging of histamine itself in living cells.

Original language	English
Pages (from-to)	6708-6711
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	20
Issue number	22
DOIs	https://doi.org/10.1016/j.bmcl.2010.09.003
Publication status	Published - Nov 15 2010

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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abstract = "A novel fluorescent probe composed of two moieties, Nile Red and an iminodiacetic acid-Ni2+ complex, for the detection of histamine in living cells is described. The probe was successfully applied to visualizing histamine in RAW264 cells, representing the first demonstration of the imaging of histamine itself in living cells.",

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