Abstract
It is necessary to use complicated myocardial cell model and heart model to evaluate the regional energy production and consumption which leads to the unrealistic computational time. In this research, a left ventricle (LV) simulation model was constructed which includes accurate myocardial cell model. In order to simulate the model in realistic time, we introduced an approximation model of the crossbridge model which can be calculated with weak coupling calculation. The LV model was combined with a circulation model to validate the proposed model by calculating the hemodynamics parameters and ventricular energetics indices. The ESPVR (End Systolic Pressure Volume Relation) showed linear relation, and also the PVA - ATP consumption relation showed linear relation which are widely known as the physiological characteristics of mammalian hearts. From these results, we can say that the model can be used as a model for physiological simulation experiments which are related to the ventricular energetics.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 |
| Pages | 957-960 |
| Number of pages | 4 |
| Publication status | Published - Dec 1 2008 |
| Externally published | Yes |
| Event | 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada Duration: Aug 20 2008 → Aug 25 2008 |
Publication series
| Name | Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology" |
|---|
Other
| Other | 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 |
|---|---|
| Country | Canada |
| City | Vancouver, BC |
| Period | 8/20/08 → 8/25/08 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Computer Vision and Pattern Recognition
- Signal Processing
- Biomedical Engineering
- Health Informatics
Cite this
An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model. / Amano, Akira; Takada, Yasuhiro; Lu, Jianyin; Shimayoshi, Takao; Matsuda, Tetsuya.
Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. p. 957-960 4649313 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model
AU - Amano, Akira
AU - Takada, Yasuhiro
AU - Lu, Jianyin
AU - Shimayoshi, Takao
AU - Matsuda, Tetsuya
PY - 2008/12/1
Y1 - 2008/12/1
N2 - It is necessary to use complicated myocardial cell model and heart model to evaluate the regional energy production and consumption which leads to the unrealistic computational time. In this research, a left ventricle (LV) simulation model was constructed which includes accurate myocardial cell model. In order to simulate the model in realistic time, we introduced an approximation model of the crossbridge model which can be calculated with weak coupling calculation. The LV model was combined with a circulation model to validate the proposed model by calculating the hemodynamics parameters and ventricular energetics indices. The ESPVR (End Systolic Pressure Volume Relation) showed linear relation, and also the PVA - ATP consumption relation showed linear relation which are widely known as the physiological characteristics of mammalian hearts. From these results, we can say that the model can be used as a model for physiological simulation experiments which are related to the ventricular energetics.
AB - It is necessary to use complicated myocardial cell model and heart model to evaluate the regional energy production and consumption which leads to the unrealistic computational time. In this research, a left ventricle (LV) simulation model was constructed which includes accurate myocardial cell model. In order to simulate the model in realistic time, we introduced an approximation model of the crossbridge model which can be calculated with weak coupling calculation. The LV model was combined with a circulation model to validate the proposed model by calculating the hemodynamics parameters and ventricular energetics indices. The ESPVR (End Systolic Pressure Volume Relation) showed linear relation, and also the PVA - ATP consumption relation showed linear relation which are widely known as the physiological characteristics of mammalian hearts. From these results, we can say that the model can be used as a model for physiological simulation experiments which are related to the ventricular energetics.
UR - http://www.scopus.com/inward/record.url?scp=61849119447&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=61849119447&partnerID=8YFLogxK
M3 - Conference contribution
C2 - 19162816
AN - SCOPUS:61849119447
SN - 9781424418152
T3 - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"
SP - 957
EP - 960
BT - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
ER -