An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model

Akira Amano, Yasuhiro Takada, Jianyin Lu, Takao Shimayoshi, Tetsuya Matsuda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Citations (Scopus)

Abstract

It is necessary to use complicated myocardial cell model and heart model to evaluate the regional energy production and consumption which leads to the unrealistic computational time. In this research, a left ventricle (LV) simulation model was constructed which includes accurate myocardial cell model. In order to simulate the model in realistic time, we introduced an approximation model of the crossbridge model which can be calculated with weak coupling calculation. The LV model was combined with a circulation model to validate the proposed model by calculating the hemodynamics parameters and ventricular energetics indices. The ESPVR (End Systolic Pressure Volume Relation) showed linear relation, and also the PVA - ATP consumption relation showed linear relation which are widely known as the physiological characteristics of mammalian hearts. From these results, we can say that the model can be used as a model for physiological simulation experiments which are related to the ventricular energetics.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages957-960
Number of pages4
Publication statusPublished - Dec 1 2008
Externally publishedYes
Event30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, Canada
Duration: Aug 20 2008Aug 25 2008

Publication series

NameProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

Other

Other30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
CountryCanada
CityVancouver, BC
Period8/20/088/25/08

Fingerprint

Heart Ventricles
Adenosine Triphosphate
Hemodynamics
Blood Pressure
Research
Adenosinetriphosphate

All Science Journal Classification (ASJC) codes

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Amano, A., Takada, Y., Lu, J., Shimayoshi, T., & Matsuda, T. (2008). An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 957-960). [4649313] (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").

An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model. / Amano, Akira; Takada, Yasuhiro; Lu, Jianyin; Shimayoshi, Takao; Matsuda, Tetsuya.

Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. p. 957-960 4649313 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Amano, A, Takada, Y, Lu, J, Shimayoshi, T & Matsuda, T 2008, An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model. in Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08., 4649313, Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology", pp. 957-960, 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08, Vancouver, BC, Canada, 8/20/08.
Amano A, Takada Y, Lu J, Shimayoshi T, Matsuda T. An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. p. 957-960. 4649313. (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").
Amano, Akira ; Takada, Yasuhiro ; Lu, Jianyin ; Shimayoshi, Takao ; Matsuda, Tetsuya. / An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model. Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08. 2008. pp. 957-960 (Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology").
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