An enantiocontrolled total synthesis of (-)-xanthorrhizol

Kenji Sato, Toshikazu Bando, Mitsuru Shindo, Kozo Shishido

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

An efficient and enantiocontrolled total synthesis of natural (-)- xanthorrhizol (3) has been accomplished by employing the lipase-mediated asymmetric acetylation of the σ-symmetrical prochiral 2-aryl-1,3-propanediol (7) leading to the formation of the optically enriched monoacetate (6) as the key step.

Original languageEnglish
Pages (from-to)11-15
Number of pages5
JournalHeterocycles
Volume50
Issue number1
Publication statusPublished - Jan 1 1999

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Acetylation
Lipase
xanthorrhizol
1,3-propanediol

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Cite this

Sato, K., Bando, T., Shindo, M., & Shishido, K. (1999). An enantiocontrolled total synthesis of (-)-xanthorrhizol. Heterocycles, 50(1), 11-15.

An enantiocontrolled total synthesis of (-)-xanthorrhizol. / Sato, Kenji; Bando, Toshikazu; Shindo, Mitsuru; Shishido, Kozo.

In: Heterocycles, Vol. 50, No. 1, 01.01.1999, p. 11-15.

Research output: Contribution to journalArticle

Sato, K, Bando, T, Shindo, M & Shishido, K 1999, 'An enantiocontrolled total synthesis of (-)-xanthorrhizol', Heterocycles, vol. 50, no. 1, pp. 11-15.
Sato K, Bando T, Shindo M, Shishido K. An enantiocontrolled total synthesis of (-)-xanthorrhizol. Heterocycles. 1999 Jan 1;50(1):11-15.
Sato, Kenji ; Bando, Toshikazu ; Shindo, Mitsuru ; Shishido, Kozo. / An enantiocontrolled total synthesis of (-)-xanthorrhizol. In: Heterocycles. 1999 ; Vol. 50, No. 1. pp. 11-15.
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