An enantiocontrolled total synthesis of (-)-xanthorrhizol

Kenji Sato, Toshikazu Bando, Mitsuru Shindo, Kozo Shishido

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

An efficient and enantiocontrolled total synthesis of natural (-)- xanthorrhizol (3) has been accomplished by employing the lipase-mediated asymmetric acetylation of the σ-symmetrical prochiral 2-aryl-1,3-propanediol (7) leading to the formation of the optically enriched monoacetate (6) as the key step.

Original languageEnglish
Pages (from-to)11-15
Number of pages5
JournalHeterocycles
Volume50
Issue number1
DOIs
Publication statusPublished - Jan 1 1999
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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