An explicit signature of balancing selection for color-vision variation in new world monkeys

Tomohide Hiwatashi, Yugo Okabe, Toko Tsutsui, Chihiro Hiramatsu, Amanda D. Melin, Hiroki Oota, Colleen M. Schaffner, Filippo Aureli, Linda M. Fedigan, Hideki Innan, Shoji Kawamura

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Color vision is an important characteristic of primates and, intriguingly, Neotropical monkeys are highly polymorphic for this trait. Recent field studies have challenged the conventional view that trichromatic color vision is more adaptive than dichromatic color vision. No study has investigated the pattern of genetic variation in the long to middle wavelength-sensitive (L-M or red-green) opsin gene as compared with that of other genomic regions (neutral references) in wild populations of New World monkeys to look for the signature of natural selection. Here, we report such a study conducted on spider monkeys and capuchin monkeys inhabiting Santa Rosa National Park, Costa Rica. The nucleotide sequence of the L-M opsin gene was more polymorphic than the sequences of the neutral references, although the opsin-gene sequences were not more divergent between the two species than were the sequences of the neutral references. In a coalescence simulation that took into account the observed nucleotide diversity of the neutral references, the Tajima's D value of the L-M opsin gene deviated significantly in a positive direction from the expected range. These results are the first to statistically demonstrate balancing selection acting on the polymorphic L-M opsin gene of New World monkeys. Taking the results of behavioral and genetic studies together, the balancing selection we detected may indicate that coexistence of different color-vision types in the same population, also characteristic of humans, is adaptive.

Original languageEnglish
Pages (from-to)453-464
Number of pages12
JournalMolecular Biology and Evolution
Volume27
Issue number2
DOIs
Publication statusPublished - Feb 1 2010

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Platyrrhini
opsin
Color Vision
Cebidae
color vision
Opsins
gene
Genes
monkeys
genes
Atelinae
Cebus
Behavioral Genetics
nucleotide sequences
Costa Rica
population characteristics
Genetic Selection
Population Characteristics
coalescence
wild population

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

Cite this

An explicit signature of balancing selection for color-vision variation in new world monkeys. / Hiwatashi, Tomohide; Okabe, Yugo; Tsutsui, Toko; Hiramatsu, Chihiro; Melin, Amanda D.; Oota, Hiroki; Schaffner, Colleen M.; Aureli, Filippo; Fedigan, Linda M.; Innan, Hideki; Kawamura, Shoji.

In: Molecular Biology and Evolution, Vol. 27, No. 2, 01.02.2010, p. 453-464.

Research output: Contribution to journalArticle

Hiwatashi, T, Okabe, Y, Tsutsui, T, Hiramatsu, C, Melin, AD, Oota, H, Schaffner, CM, Aureli, F, Fedigan, LM, Innan, H & Kawamura, S 2010, 'An explicit signature of balancing selection for color-vision variation in new world monkeys', Molecular Biology and Evolution, vol. 27, no. 2, pp. 453-464. https://doi.org/10.1093/molbev/msp262
Hiwatashi, Tomohide ; Okabe, Yugo ; Tsutsui, Toko ; Hiramatsu, Chihiro ; Melin, Amanda D. ; Oota, Hiroki ; Schaffner, Colleen M. ; Aureli, Filippo ; Fedigan, Linda M. ; Innan, Hideki ; Kawamura, Shoji. / An explicit signature of balancing selection for color-vision variation in new world monkeys. In: Molecular Biology and Evolution. 2010 ; Vol. 27, No. 2. pp. 453-464.
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