An ion-gate response of the glutathione monolayer assembly formed on a gold electrode. Part 1. The effect of pH, K+ and Ca2+

Ko Takehara, Yasushi Ide, Makoto Aihara, Eiko Obuchi

Research output: Contribution to journalArticle

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Abstract

The electrochemical behavior of the self-assembled glutathione (GSH) monolayer formed on a gold electrode was studied in aqueous Fe(CN)63- solution in order to characterize the ion permeation properties of this monolayer assembly. It was found that the GSH monolayer showed ion-gate behavior for the permeation of Fe(CN)63- probe ion. At pH 5.3, the monolayer assembly strongly hindered the electron transfer between the gold surface and the Fe(CN)63- ion in solution. In contrast, the electron transfer was drastically improved at pH 2.9. The electron transfer was also found to improve with increasing Ca2+ concentration. The rate constant of Fe(CN)63- reduction increased linearly with Ca2+ concentration. The ion-gate behavior of the GSH monolayer is discussed in terms of the conformational change in GSH caused by the coordination with Ca2+ and the electrostatic interaction between GSH and Fe(CN)63-.

Original languageEnglish
Pages (from-to)103-111
Number of pages9
JournalBioelectrochemistry and Bioenergetics
Volume29
Issue number1
DOIs
Publication statusPublished - Jan 1 1992

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glutathione
Gold
Glutathione
Monolayers
Electrodes
assembly
Ions
gold
electron transfer
electrodes
Electrons
ions
Permeation
ion probes
Coulomb interactions
Static Electricity
electrostatics
Rate constants
interactions

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Physical and Theoretical Chemistry
  • Electrochemistry

Cite this

An ion-gate response of the glutathione monolayer assembly formed on a gold electrode. Part 1. The effect of pH, K+ and Ca2+. / Takehara, Ko; Ide, Yasushi; Aihara, Makoto; Obuchi, Eiko.

In: Bioelectrochemistry and Bioenergetics, Vol. 29, No. 1, 01.01.1992, p. 103-111.

Research output: Contribution to journalArticle

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