An NcoI polymorphism in the human complement component 7 (C7) gene

Takahiko Horiuchi, Hiroaki Nishizaka, Hiroshi Tsukamoto, Shin Ichi Harashima, Takuya Sawabe, Chika Morita, Yoshiyuki Niho

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

A novel polymorphic site has been found in the 3' untranslated region (UTR) of the human complement component 7 (C7) gene. The polymorphic site at 14-bp downstream from the TAG stop codon was either C or A (Nco I-digested), with allele frequencies of 0.660 and 0.340. This NcoI polymorphism would be useful to perform a DNA marker haplotype study in patients with deficiencies of the complement genes, such as C6, C7, C9, which are located closely on chromosome 5p13.

Original languageEnglish
Pages (from-to)270-271
Number of pages2
JournalJournal of Human Genetics
Volume44
Issue number4
DOIs
Publication statusPublished - 1999

All Science Journal Classification (ASJC) codes

  • Genetics
  • Genetics(clinical)

Fingerprint Dive into the research topics of 'An NcoI polymorphism in the human complement component 7 (C7) gene'. Together they form a unique fingerprint.

Cite this