TY - JOUR
T1 - An update on novel oral anticoagulants
AU - Ago, Tetsuro
AU - Wakisaka, Yoshinobu
AU - Kuroda, Junya
N1 - Publisher Copyright:
© 2015 Japanese Congress of Neurological Surgeons. All rights reserved.
PY - 2015
Y1 - 2015
N2 - Stroke is the leading cause of bedridden and dependent patients worldwide. Since cardioembolic stroke, the most severe subtype of ischemic stroke, often develops in subjects with atrial fibrillation, optimal anticoagulation therapy should be administered to those with atrial fibrillation, particularly in the elderly. Recently, several novel oral anticoagulants(NOAC)have been developed for the prevention of cardioembolic stroke. Accordingly, it is important to have thorough understanding of these NOACs, including both their individual characteristics and their proper administration protocols. In this review, we discuss the present status and cautionary notes for using anticoagulation therapy in the prevention of cardioembolic stroke.
AB - Stroke is the leading cause of bedridden and dependent patients worldwide. Since cardioembolic stroke, the most severe subtype of ischemic stroke, often develops in subjects with atrial fibrillation, optimal anticoagulation therapy should be administered to those with atrial fibrillation, particularly in the elderly. Recently, several novel oral anticoagulants(NOAC)have been developed for the prevention of cardioembolic stroke. Accordingly, it is important to have thorough understanding of these NOACs, including both their individual characteristics and their proper administration protocols. In this review, we discuss the present status and cautionary notes for using anticoagulation therapy in the prevention of cardioembolic stroke.
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U2 - 10.7887/jcns.24.220
DO - 10.7887/jcns.24.220
M3 - Article
AN - SCOPUS:84928593942
VL - 24
SP - 220
EP - 225
JO - Japanese Journal of Neurosurgery
JF - Japanese Journal of Neurosurgery
SN - 0917-950X
IS - 4
ER -