Analysis of gastric cancer with cDNA microarray

Naotsugu Haraguchi, Hiroshi Inoue, Koshi Mimori, Fumiaki Tanaka, Tohru Utsunomiya, Kouji Yoshikawa, Masaki Mori

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Recent advances in cDNA microarray techniques have enabled us to study the expression of many genes simultaneously. As gastric cancer remains one of the most common cancers in Japan, we studied gene expression profiles in gastric cancer by cDNA microarray analysis to determine if it would be clinically useful. We demonstrated two points. First, cDNA microarray might be useful as a prognostic indicator. However, there remain several important problems to be solved and these are discussed. Second, laser microdissection plus cDNA microarray might be useful in determining the specific genes that correlate to cancer metastasis or histological subtype. We review the pros and cons for cDNA microarray analysis in the context of gastric cancer.

Original languageEnglish
JournalCancer chemotherapy and pharmacology
Volume54
Issue numberSUPPL. 1
DOIs
Publication statusPublished - Sep 1 2004

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Microarrays
Oligonucleotide Array Sequence Analysis
Stomach Neoplasms
Complementary DNA
Microarray Analysis
Microdissection
Genes
Transcriptome
Gene expression
Neoplasms
Japan
Lasers
Neoplasm Metastasis
Gene Expression

All Science Journal Classification (ASJC) codes

  • Oncology
  • Toxicology
  • Pharmacology
  • Cancer Research
  • Pharmacology (medical)

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Analysis of gastric cancer with cDNA microarray. / Haraguchi, Naotsugu; Inoue, Hiroshi; Mimori, Koshi; Tanaka, Fumiaki; Utsunomiya, Tohru; Yoshikawa, Kouji; Mori, Masaki.

In: Cancer chemotherapy and pharmacology, Vol. 54, No. SUPPL. 1, 01.09.2004.

Research output: Contribution to journalArticle

Haraguchi, N, Inoue, H, Mimori, K, Tanaka, F, Utsunomiya, T, Yoshikawa, K & Mori, M 2004, 'Analysis of gastric cancer with cDNA microarray', Cancer chemotherapy and pharmacology, vol. 54, no. SUPPL. 1. https://doi.org/10.1007/s00280-004-0882-2
Haraguchi N, Inoue H, Mimori K, Tanaka F, Utsunomiya T, Yoshikawa K et al. Analysis of gastric cancer with cDNA microarray. Cancer chemotherapy and pharmacology. 2004 Sep 1;54(SUPPL. 1). https://doi.org/10.1007/s00280-004-0882-2
Haraguchi, Naotsugu ; Inoue, Hiroshi ; Mimori, Koshi ; Tanaka, Fumiaki ; Utsunomiya, Tohru ; Yoshikawa, Kouji ; Mori, Masaki. / Analysis of gastric cancer with cDNA microarray. In: Cancer chemotherapy and pharmacology. 2004 ; Vol. 54, No. SUPPL. 1.
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