Analysis of small smounts of D-Amino acids and the study of their physiological functions in mammals

Kenji Hamase, Akiko Morikawa, Sachise Etoh, Yosuke Tojo, Yurika Miyoshi, Kiyoshi Zaitsu

Research output: Contribution to journalReview article

47 Citations (Scopus)

Abstract

D-Amino acids, the enantiomers of L-amino acids, are candidates to be novel physiologically active substances and the biomarkers in mammals. However, the amounts of D-amino acids in the tissues and physiological fluids are extremely small in most cases, and sensitive and selective analytical methods are needed for their determination. In the present manuscript, we review the analytical technologies including our recent advances for the determinations of small amounts of D-amino acids in mammals and the applications to clarify their physiological meanings. 2009

Original languageEnglish
Pages (from-to)961-968
Number of pages8
Journalanalytical sciences
Volume25
Issue number8
DOIs
Publication statusPublished - Aug 2009

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

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