Analysis of the risk of ischemic stroke in intracranial atherosclerotic stenosis by CBF measurement and plaque characterization

Yusuke Egashira, Koji Iihara, Tetsu Satow, Jun Takahashi, Naoaki Yamada, Susumu Miyamoto

Research output: Contribution to journalArticle

Abstract

Objective: Atherosclerotic intracranial stenosis is considered one of the major causes of ischemic stroke. We analyzed cerebral blood flow (CBF) and plaque characteristics in atherosclerotic intracranial internal carotid stenosis (iICS) patients to evaluate the risk of ischemic stroke. Methods : Since November 2003, 26 lesions in 25 patients were treated at our institution. All patients underwent plaque characterization using MRI and CBF evaluation using SPECT. Results : Only one lesion caused severe hemodynamic insufficiency and two patients had vulnerable plaque in their stenotic segments. Tandem lesions were existent in 9 lesions (35%) and contralateral lesions were existent in 11 patients (44%). Conclusion : Based on the CBF and plaque imaging results, the risk of ischemic stroke due to iICS itself is not thought to be so high as previously reported.

Original languageEnglish
Pages (from-to)502-508
Number of pages7
JournalJapanese Journal of Neurosurgery
Volume18
Issue number7
DOIs
Publication statusPublished - Jan 1 2009
Externally publishedYes

Fingerprint

Cerebrovascular Circulation
Pathologic Constriction
Stroke
Carotid Stenosis
Single-Photon Emission-Computed Tomography
Hemodynamics

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Cite this

Analysis of the risk of ischemic stroke in intracranial atherosclerotic stenosis by CBF measurement and plaque characterization. / Egashira, Yusuke; Iihara, Koji; Satow, Tetsu; Takahashi, Jun; Yamada, Naoaki; Miyamoto, Susumu.

In: Japanese Journal of Neurosurgery, Vol. 18, No. 7, 01.01.2009, p. 502-508.

Research output: Contribution to journalArticle

Egashira, Yusuke ; Iihara, Koji ; Satow, Tetsu ; Takahashi, Jun ; Yamada, Naoaki ; Miyamoto, Susumu. / Analysis of the risk of ischemic stroke in intracranial atherosclerotic stenosis by CBF measurement and plaque characterization. In: Japanese Journal of Neurosurgery. 2009 ; Vol. 18, No. 7. pp. 502-508.
@article{6dd61d4450454d85a07c722b87315862,
title = "Analysis of the risk of ischemic stroke in intracranial atherosclerotic stenosis by CBF measurement and plaque characterization",
abstract = "Objective: Atherosclerotic intracranial stenosis is considered one of the major causes of ischemic stroke. We analyzed cerebral blood flow (CBF) and plaque characteristics in atherosclerotic intracranial internal carotid stenosis (iICS) patients to evaluate the risk of ischemic stroke. Methods : Since November 2003, 26 lesions in 25 patients were treated at our institution. All patients underwent plaque characterization using MRI and CBF evaluation using SPECT. Results : Only one lesion caused severe hemodynamic insufficiency and two patients had vulnerable plaque in their stenotic segments. Tandem lesions were existent in 9 lesions (35{\%}) and contralateral lesions were existent in 11 patients (44{\%}). Conclusion : Based on the CBF and plaque imaging results, the risk of ischemic stroke due to iICS itself is not thought to be so high as previously reported.",
author = "Yusuke Egashira and Koji Iihara and Tetsu Satow and Jun Takahashi and Naoaki Yamada and Susumu Miyamoto",
year = "2009",
month = "1",
day = "1",
doi = "10.7887/jcns.18.502",
language = "English",
volume = "18",
pages = "502--508",
journal = "Japanese Journal of Neurosurgery",
issn = "0917-950X",
publisher = "Japanese Congress of Neurological Surgeons",
number = "7",

}

TY - JOUR

T1 - Analysis of the risk of ischemic stroke in intracranial atherosclerotic stenosis by CBF measurement and plaque characterization

AU - Egashira, Yusuke

AU - Iihara, Koji

AU - Satow, Tetsu

AU - Takahashi, Jun

AU - Yamada, Naoaki

AU - Miyamoto, Susumu

PY - 2009/1/1

Y1 - 2009/1/1

N2 - Objective: Atherosclerotic intracranial stenosis is considered one of the major causes of ischemic stroke. We analyzed cerebral blood flow (CBF) and plaque characteristics in atherosclerotic intracranial internal carotid stenosis (iICS) patients to evaluate the risk of ischemic stroke. Methods : Since November 2003, 26 lesions in 25 patients were treated at our institution. All patients underwent plaque characterization using MRI and CBF evaluation using SPECT. Results : Only one lesion caused severe hemodynamic insufficiency and two patients had vulnerable plaque in their stenotic segments. Tandem lesions were existent in 9 lesions (35%) and contralateral lesions were existent in 11 patients (44%). Conclusion : Based on the CBF and plaque imaging results, the risk of ischemic stroke due to iICS itself is not thought to be so high as previously reported.

AB - Objective: Atherosclerotic intracranial stenosis is considered one of the major causes of ischemic stroke. We analyzed cerebral blood flow (CBF) and plaque characteristics in atherosclerotic intracranial internal carotid stenosis (iICS) patients to evaluate the risk of ischemic stroke. Methods : Since November 2003, 26 lesions in 25 patients were treated at our institution. All patients underwent plaque characterization using MRI and CBF evaluation using SPECT. Results : Only one lesion caused severe hemodynamic insufficiency and two patients had vulnerable plaque in their stenotic segments. Tandem lesions were existent in 9 lesions (35%) and contralateral lesions were existent in 11 patients (44%). Conclusion : Based on the CBF and plaque imaging results, the risk of ischemic stroke due to iICS itself is not thought to be so high as previously reported.

UR - http://www.scopus.com/inward/record.url?scp=73349127436&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=73349127436&partnerID=8YFLogxK

U2 - 10.7887/jcns.18.502

DO - 10.7887/jcns.18.502

M3 - Article

AN - SCOPUS:73349127436

VL - 18

SP - 502

EP - 508

JO - Japanese Journal of Neurosurgery

JF - Japanese Journal of Neurosurgery

SN - 0917-950X

IS - 7

ER -