Analysis of the underlying mechanism of frank-starling law of a constructive hemodynamics model

Mitsuharu Mishima, Takao Shimayoshi, Akira Amano, Tetsuya Matsuda

Research output: Contribution to conferencePaper

Abstract

Frank-Starling law, which describes a relation between cardiac contraction energy and end-diastolic volume, is of importance, but the detailed mechanism is not quantitatively understood yet. In this paper, the mechanism of a linear relation between end-diastolic volume and end-systolic pressure as a part of Frank-Starling law is analyzed by means of computer simulation. A hemodynamics model, which is constructed by composing a vascular system model, a left ventricular dynamics model and a myocardial cell model, reproduced a linear relation between end-diastolic volume and end-systolic pressure successfully. In this paper, the simulation results and the detailed analysis are reported.

Original languageEnglish
Publication statusPublished - 2009
Externally publishedYes
EventAsia Simulation Conference 2009, JSST 2009 - Shiga, Japan
Duration: Oct 7 2009Oct 9 2009

Other

OtherAsia Simulation Conference 2009, JSST 2009
CountryJapan
CityShiga
Period10/7/0910/9/09

All Science Journal Classification (ASJC) codes

  • Modelling and Simulation

Fingerprint Dive into the research topics of 'Analysis of the underlying mechanism of frank-starling law of a constructive hemodynamics model'. Together they form a unique fingerprint.

  • Cite this

    Mishima, M., Shimayoshi, T., Amano, A., & Matsuda, T. (2009). Analysis of the underlying mechanism of frank-starling law of a constructive hemodynamics model. Paper presented at Asia Simulation Conference 2009, JSST 2009, Shiga, Japan.