Abstract
Frank-Starling law, which describes a relation between cardiac contraction energy and end-diastolic volume, is of importance, but the detailed mechanism is not quantitatively understood yet. In this paper, the mechanism of a linear relation between end-diastolic volume and end-systolic pressure as a part of Frank-Starling law is analyzed by means of computer simulation. A hemodynamics model, which is constructed by composing a vascular system model, a left ventricular dynamics model and a myocardial cell model, reproduced a linear relation between end-diastolic volume and end-systolic pressure successfully. In this paper, the simulation results and the detailed analysis are reported.
| Original language | English |
|---|---|
| Publication status | Published - Jan 1 2009 |
| Externally published | Yes |
| Event | Asia Simulation Conference 2009, JSST 2009 - Shiga, Japan Duration: Oct 7 2009 → Oct 9 2009 |
Other
| Other | Asia Simulation Conference 2009, JSST 2009 |
|---|---|
| Country | Japan |
| City | Shiga |
| Period | 10/7/09 → 10/9/09 |
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All Science Journal Classification (ASJC) codes
- Modelling and Simulation
Cite this
Analysis of the underlying mechanism of frank-starling law of a constructive hemodynamics model. / Mishima, Mitsuharu; Shimayoshi, Takao; Amano, Akira; Matsuda, Tetsuya.
2009. Paper presented at Asia Simulation Conference 2009, JSST 2009, Shiga, Japan.Research output: Contribution to conference › Paper
}
TY - CONF
T1 - Analysis of the underlying mechanism of frank-starling law of a constructive hemodynamics model
AU - Mishima, Mitsuharu
AU - Shimayoshi, Takao
AU - Amano, Akira
AU - Matsuda, Tetsuya
PY - 2009/1/1
Y1 - 2009/1/1
N2 - Frank-Starling law, which describes a relation between cardiac contraction energy and end-diastolic volume, is of importance, but the detailed mechanism is not quantitatively understood yet. In this paper, the mechanism of a linear relation between end-diastolic volume and end-systolic pressure as a part of Frank-Starling law is analyzed by means of computer simulation. A hemodynamics model, which is constructed by composing a vascular system model, a left ventricular dynamics model and a myocardial cell model, reproduced a linear relation between end-diastolic volume and end-systolic pressure successfully. In this paper, the simulation results and the detailed analysis are reported.
AB - Frank-Starling law, which describes a relation between cardiac contraction energy and end-diastolic volume, is of importance, but the detailed mechanism is not quantitatively understood yet. In this paper, the mechanism of a linear relation between end-diastolic volume and end-systolic pressure as a part of Frank-Starling law is analyzed by means of computer simulation. A hemodynamics model, which is constructed by composing a vascular system model, a left ventricular dynamics model and a myocardial cell model, reproduced a linear relation between end-diastolic volume and end-systolic pressure successfully. In this paper, the simulation results and the detailed analysis are reported.
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