Anaplastic large cell ki-1 lymphoma in the central nervous system: Report of an autopsy case

M. Miyazono, T. Iwaki, J. Tateishi, M. Fukui

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8 Citations (Scopus)


A 45-year old immunocompetent man presented with multiple lesions in the brain. A histological examination of the tumors showed a diffuse infiltrate of lymphoid cells with cellular polymorphism and of multinucleated giant cells. These cells were immunolabeled with antibodies against B cell lineage and with a monoclonal antibody, Ber-H2 (CD30), which showed the presence of Ki-1 antigen. Recently, among systemic non-Hodgkin's lymphomas, attention has been given to Ki-1-positive lymphomas, which have been incorporated in the up-dated Kiel classification. We report here a case of Ki-1-positive lymphoma arising in the CNS and review previously reported cases.

Original languageEnglish
Pages (from-to)577-580
Number of pages4
JournalActa neuropathologica
Issue number5
Publication statusPublished - Oct 1 1992


All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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