TY - JOUR
T1 - Ancient Jomon genome sequence analysis sheds light on migration patterns of early East Asian populations
AU - Gakuhari, Takashi
AU - Nakagome, Shigeki
AU - Rasmussen, Simon
AU - Allentoft, Morten E.
AU - Sato, Takehiro
AU - Korneliussen, Thorfinn
AU - Chuinneagáin, Blánaid Ní
AU - Matsumae, Hiromi
AU - Koganebuchi, Kae
AU - Schmidt, Ryan
AU - Mizushima, Souichiro
AU - Kondo, Osamu
AU - Shigehara, Nobuo
AU - Yoneda, Minoru
AU - Kimura, Ryosuke
AU - Ishida, Hajime
AU - Masuyama, Tadayuki
AU - Yamada, Yasuhiro
AU - Tajima, Atsushi
AU - Shibata, Hiroki
AU - Toyoda, Atsushi
AU - Tsurumoto, Toshiyuki
AU - Wakebe, Tetsuaki
AU - Shitara, Hiromi
AU - Hanihara, Tsunehiko
AU - Willerslev, Eske
AU - Sikora, Martin
AU - Oota, Hiroki
N1 - Funding Information:
The excavation of the Ikawazu Jomon individual was supported by Grant-in-Aid for Scientific Research (B) (25284157) to Y.Y. The Ikawazu Jomon genome project was organized by H.I., and T.H. & H.O. who were supported by MEXT KAKENHI Grant Numbers 16H06408 and 17H05132, by Grant-in-Aid for Scientific Research on Innovative Areas (Cultural History of Paleoasia), and by Grant-in-Aid for Challenging Exploratory Research (23657167) and for Scientific Research (B) (17H03738). The Ika-wazu Jomon genome sequencing was supported by JSPS KAKENHI Grant Number 16H06279 to A.To., and partly supported in the CHOZEN project in Kanazawa University, and in the Cooperative Research Project Program of the Medical Institute of Bioregulation, Kyushu University. Computations for the Ikawazu Jomon genome were partially performed on the NIG supercomputer at ROIS National Institute of Genetics.
Publisher Copyright:
© 2020, The Author(s).
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Anatomically modern humans reached East Asia more than 40,000 years ago. However, key questions still remain unanswered with regard to the route(s) and the number of wave(s) in the dispersal into East Eurasia. Ancient genomes at the edge of the region may elucidate a more detailed picture of the peopling of East Eurasia. Here, we analyze the whole-genome sequence of a 2,500-year-old individual (IK002) from the main-island of Japan that is characterized with a typical Jomon culture. The phylogenetic analyses support multiple waves of migration, with IK002 forming a basal lineage to the East and Northeast Asian genomes examined, likely representing some of the earliest-wave migrants who went north from Southeast Asia to East Asia. Furthermore, IK002 shows strong genetic affinity with the indigenous Taiwan aborigines, which may support a coastal route of the Jomon-ancestry migration. This study highlights the power of ancient genomics to provide new insights into the complex history of human migration into East Eurasia.
AB - Anatomically modern humans reached East Asia more than 40,000 years ago. However, key questions still remain unanswered with regard to the route(s) and the number of wave(s) in the dispersal into East Eurasia. Ancient genomes at the edge of the region may elucidate a more detailed picture of the peopling of East Eurasia. Here, we analyze the whole-genome sequence of a 2,500-year-old individual (IK002) from the main-island of Japan that is characterized with a typical Jomon culture. The phylogenetic analyses support multiple waves of migration, with IK002 forming a basal lineage to the East and Northeast Asian genomes examined, likely representing some of the earliest-wave migrants who went north from Southeast Asia to East Asia. Furthermore, IK002 shows strong genetic affinity with the indigenous Taiwan aborigines, which may support a coastal route of the Jomon-ancestry migration. This study highlights the power of ancient genomics to provide new insights into the complex history of human migration into East Eurasia.
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U2 - 10.1038/s42003-020-01162-2
DO - 10.1038/s42003-020-01162-2
M3 - Article
C2 - 32843717
AN - SCOPUS:85089818067
VL - 3
JO - Communications Biology
JF - Communications Biology
SN - 2399-3642
IS - 1
M1 - 437
ER -