Anesthetic management for a patient with multiple sclerosis at exacerbation stage under general anesthesia

Koichi Yamashita, Takeshi Yokoyama, Hirofumi Tokai, Yasuhiro Imazu, Masakazu Lee, Masanobu Manabe

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A 39-year-old woman with multiple sclerosis (MS) at exacerbation stage underwent dilatation and curettage. MS is characterized by chronic inflammation, demyelination, and gliosis in the central nervous system. Surgical stress often induces exacerbation of MS symptoms. Therefore, deep anesthesia is required for anesthetic management in cases of MS. We monitored electroencephalograph (EEG), spectral edge frequency 90 (SEF 90), spectral median frequency (SMF) and δ-amplitude for depth of anesthesia using pEEG™ (Dräger, Germany). In this case, anesthesia was induced with sevoflurane and gradually increased to 5% in oxygen 4 l · min-1 and maintained with sevoflurane 2-3% in 2 nitrous oxide l · min-1 and 2 l · min-1 oxygen. Surgery was completed and no spike wave was observed by pEEG™ monitoring during surgery. In conclusion, sevoflurane anesthesia was useful for a patient with MS during exacerbation stage.

Original languageEnglish
Pages (from-to)521-523
Number of pages3
JournalJapanese Journal of Anesthesiology
Volume52
Issue number5
Publication statusPublished - May 1 2003
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Anesthesiology and Pain Medicine

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