Anti-allergic activity of lotus root (Nelumbo nucifera) powder in TDI-sensitized nasal allergy model mice

Mayumi Kaneyasu, Maki Nagata, Hiromi Ikeda, Koichiro Ohnuki, Kuniyoshi Shimizu

Research output: Contribution to journalArticle


Lotus root (Nelumbo nucifera) is a popular food in Japan and southeast Asia. It is reported that lotus root includes dietary fiber, vitamin C, and abundant polyphenolic compounds. In Chinese medicine, lotus powder is also utilized in anti-tussive or anti-inflammatory drugs. In this study, we focused on the effects of lotus root powder on allergy symptoms in mice. First, we assessed nasal allergy symptoms in 2,4-diisocyanic acid toluene (TDI)-sensitized nasal allergy model mice. We found that lotus root powder alleviated nasal allergy symptoms in the mice. In addition, we estimated serum inflammatory parameters such as serum total IgE, histamine, and leukotriene B4. Lotus root powder intake significantly decreased serum total IgE and leukotriene B4 compared with standard food intake. We suggest that lotus root powder intake may alleviate allergic symptoms.

Original languageEnglish
Pages (from-to)968-978
Number of pages11
JournalFood and Agricultural Immunology
Issue number1
Publication statusPublished - Jan 1 2019


All Science Journal Classification (ASJC) codes

  • Food Science
  • Immunology
  • Agronomy and Crop Science

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