Antitermite activity of β-caryophyllene epoxide and episulfide

Tatsuya Ashitani, Norihisa Kusumoto, Anna Karin Borg-Karlson, Koki Fujita, Koetsu Takahashi

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Caryophyllene-6,7-epoxide and caryophyllene-6,7-episulfide can be easily synthesized from β-caryophyllene by autoxidation or episulfidation. The bioactivities of β-caryophyllene and its derivatives were investigated against the subterranean termite Reticulitermes speratus Kolbe. The antifeedant, feeding, and termiticidal activities of each compound were tested using no-choice, dual-choice, and non-contact methods. Antitermitic activities were not shown by β-caryophyllene, but were observed for the oxide and sulfide derivatives. Caryophyllene- 6,7-episulfide showed especially high antifeedant and termiticidal activities. Thus, naturally abundant, non-bioactive β-caryophyllene can be easily converted into an antitermite reagent via a non-biological process.

Original languageEnglish
Pages (from-to)302-306
Number of pages5
JournalZeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume68 C
Issue number7-8
Publication statusPublished - 2013

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)


Dive into the research topics of 'Antitermite activity of β-caryophyllene epoxide and episulfide'. Together they form a unique fingerprint.

Cite this