Abstract
Case report: It is well known that magnetic resonance imaging (MRI) findings of focal cortical dysplasia (FCD) can change with maturation of myelination. In this paper, we report a patient with intractable epilepsy and negative MRI at the age of 2.5 years, after completion of myelination. Follow-up MRI at the age of 6 years revealed typical FCD findings in the right frontal lobe. During these 3.5 years, electroencephalogram (EEG) consistently depicted an area of irritation in accordance with de novo MRI findings. Intraoperative electrocorticogram showed frequent paroxysmal activity in the right frontal lobe; excision of the epileptogenic cortex resulted in a reduction in seizures. Conclusion: It is possible that FCD becomes apparent on MRI even after maturation of myelination; thus, repeated MRI is recommended while EEG continues to demonstrate focal findings.
| Original language | English |
|---|---|
| Pages (from-to) | 269-273 |
| Number of pages | 5 |
| Journal | Child's Nervous System |
| Volume | 24 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 1 2008 |
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All Science Journal Classification (ASJC) codes
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology
Cite this
Appearance of focal cortical dysplasia on serial MRI after maturation of myelination. / Yoshida, Fumiaki; Morioka, Takato; Hashiguchi, Kimiaki; Miyagi, Yasushi; Nagata, Shinji; Yamaguchi, Yui; Ohfu, Masaharu; Sasaki, Tomio.
In: Child's Nervous System, Vol. 24, No. 2, 01.02.2008, p. 269-273.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Appearance of focal cortical dysplasia on serial MRI after maturation of myelination
AU - Yoshida, Fumiaki
AU - Morioka, Takato
AU - Hashiguchi, Kimiaki
AU - Miyagi, Yasushi
AU - Nagata, Shinji
AU - Yamaguchi, Yui
AU - Ohfu, Masaharu
AU - Sasaki, Tomio
PY - 2008/2/1
Y1 - 2008/2/1
N2 - Case report: It is well known that magnetic resonance imaging (MRI) findings of focal cortical dysplasia (FCD) can change with maturation of myelination. In this paper, we report a patient with intractable epilepsy and negative MRI at the age of 2.5 years, after completion of myelination. Follow-up MRI at the age of 6 years revealed typical FCD findings in the right frontal lobe. During these 3.5 years, electroencephalogram (EEG) consistently depicted an area of irritation in accordance with de novo MRI findings. Intraoperative electrocorticogram showed frequent paroxysmal activity in the right frontal lobe; excision of the epileptogenic cortex resulted in a reduction in seizures. Conclusion: It is possible that FCD becomes apparent on MRI even after maturation of myelination; thus, repeated MRI is recommended while EEG continues to demonstrate focal findings.
AB - Case report: It is well known that magnetic resonance imaging (MRI) findings of focal cortical dysplasia (FCD) can change with maturation of myelination. In this paper, we report a patient with intractable epilepsy and negative MRI at the age of 2.5 years, after completion of myelination. Follow-up MRI at the age of 6 years revealed typical FCD findings in the right frontal lobe. During these 3.5 years, electroencephalogram (EEG) consistently depicted an area of irritation in accordance with de novo MRI findings. Intraoperative electrocorticogram showed frequent paroxysmal activity in the right frontal lobe; excision of the epileptogenic cortex resulted in a reduction in seizures. Conclusion: It is possible that FCD becomes apparent on MRI even after maturation of myelination; thus, repeated MRI is recommended while EEG continues to demonstrate focal findings.
UR - http://www.scopus.com/inward/record.url?scp=37749010667&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=37749010667&partnerID=8YFLogxK
U2 - 10.1007/s00381-007-0447-x
DO - 10.1007/s00381-007-0447-x
M3 - Article
C2 - 17680248
AN - SCOPUS:37749010667
VL - 24
SP - 269
EP - 273
JO - Child's Nervous System
JF - Child's Nervous System
SN - 0256-7040
IS - 2
ER -