Assignment of the absolute configuration of blasticidin A and revision of that of aflastatin A

Shohei Sakuda; Nobuaki Matsumori; Kazuo Furihata; Hiromichi Nagasawa

doi:10.1016/j.tetlet.2007.02.024

Assignment of the absolute configuration of blasticidin A and revision of that of aflastatin A

Shohei Sakuda, Nobuaki Matsumori, Kazuo Furihata, Hiromichi Nagasawa

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

The absolute configuration of blasticidin A, a strong inhibitor of aflatoxin production by Aspergillus parasiticus, was assigned by adding the data of relative configurations at its diol and pentaol moieties to previously known stereochemistry. Similarity of the NMR data of blasticidin A to those of aflastatin A allowed us to revise the stereochemistry of the diol and pentaol moieties of aflastatin A.

Original language	English
Pages (from-to)	2527-2531
Number of pages	5
Journal	Tetrahedron Letters
Volume	48
Issue number	14
DOIs	https://doi.org/10.1016/j.tetlet.2007.02.024
Publication status	Published - Apr 2 2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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AU - Furihata, Kazuo

AU - Nagasawa, Hiromichi

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