Assignment of the absolute configuration of blasticidin A and revision of that of aflastatin A

Shohei Sakuda, Nobuaki Matsumori, Kazuo Furihata, Hiromichi Nagasawa

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

The absolute configuration of blasticidin A, a strong inhibitor of aflatoxin production by Aspergillus parasiticus, was assigned by adding the data of relative configurations at its diol and pentaol moieties to previously known stereochemistry. Similarity of the NMR data of blasticidin A to those of aflastatin A allowed us to revise the stereochemistry of the diol and pentaol moieties of aflastatin A.

Original languageEnglish
Pages (from-to)2527-2531
Number of pages5
JournalTetrahedron Letters
Volume48
Issue number14
DOIs
Publication statusPublished - Apr 2 2007
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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